Brief Title: Urine Methylation Markers in UTUC

PRIMARY OUTCOMES

Primary Outcome 1 - Measure: Methylation level of urothelial-specific biomarker TRNA-Cys

Primary Outcome 1 - Timeframe: Baseline

Primary Outcome 2 - Measure: Methylation level of urothelial-specific biomarker SIM2

Primary Outcome 2 - Timeframe: 3 months

Primary Outcome 3 - Measure: Methylation level of urothelial-specific biomarker NKX1-1

Primary Outcome 3 - Timeframe: 6 months

CONDITION

• Upper Tract Urothelial Cancer

ELIGIBILITY

Inclusion Criteria:
* >=18 years

- * Primary UTUC
Exclusion Criteria:
* Patients who do not understand and/or are unwilling to sign a written informed consent

Gender: All

Minimum Age: 18 Years

Maximum Age: N/A

Healthy Volunteers: No

OFFICIAL INFORMATION

Name: Michael Abern, MD

Role: Principal Investigator

Affiliation: Duke University

Overall Contact

Name: Alireza Ghoreifinejadian, M.D.

Phone: 919-684-8111

Email: [email protected]

LOCATION