BCAN's Funded Research Awards

Svetlana Avulova, MD

Urologic Oncology Fellow

Institution:
Mayo Clinic

Research:

Sexual Function in Women Undergoing Radical Cystectomy

Summary:

Background 

The main treatment for bladder cancer is a surgery called radical cystectomy. This means the bladder is removed, and the body is given a new way to pass urine. For women, this surgery often involves removing not just the bladder, but also other organs such as part of the vagina, the uterus, ovaries, and fallopian tubes. While this is done to control the cancer, it can also have a big effect on sexual health and overall quality of life. 

What This Research Proposes to Address 

Some past studies suggest that leaving certain female organs in place during surgery may help women keep better sexual function, without making the cancer treatment less effective. However, there has not been enough research on this approach, especially when robotic surgery is used. Robotic surgery is a newer technique that may help improve recovery and outcomes, but we don’t yet know how it affects sexual health when combined with organ-sparing methods. 

This study will focus on learning which surgical choices and patient factors contribute most to sexual problems after bladder removal surgery. Researchers will use surveys directly from patients to better understand their experiences. 

Why This Research Is Important 

Sexual health is a vital part of quality of life, yet women with bladder cancer often face major challenges after surgery. By studying the connection between surgical techniques, patient experiences, and sexual function, doctors can give women clearer information before surgery. This will help women make more informed choices and prepare for life after treatment. 

The findings of this study could change how doctors talk with women about bladder cancer surgery. By learning which approaches protect sexual health the most, doctors may be able to adjust treatment plans in ways that improve both cancer control and quality of life. This research has the potential to give women better counseling, better choices, and better outcomes. 

Final Report Summary

This study looked at women’s experiences with sexual health before and after bladder surgery. Out of 124 women surveyed, most had already gone through menopause, and many had not used hormone treatments. Before surgery, about 40% said they didn’t know what to expect about sexual function, and 30% thought it would stay the same. Nearly 70% felt it was at least somewhat important to regain sexual function, with more than a quarter saying it was very important. Still, many women didn’t know when recovery might happen, and some believed it would never return. Most women also reported they had never spoken with a doctor about these concerns. 

When asked about being sexually active before surgery, only about one-third said they were. For those not active, the most common reason was a lack of interest. Researchers measured different aspects of sexual health, including interest in sex, lubrication, discomfort, and overall satisfaction. At the start, scores were generally lower than the national average. After surgery, there was a small improvement in sexual interest at three months, but this did not last at six or twelve months. For the other measures, there were no significant changes. Overall, the study found that sexual function stayed mostly the same after surgery. 

Citations:

None Reported as of August 2025

Additional Research:

None Reported as of August 2025

Project Collaborators:

NA

Project Status:
Completed