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Brief Title: An Investigational Immuno-therapy Study of Nivolumab, Compared to Placebo, in Patients With Bladder or Upper Urinary Tract Cancer, Following Surgery to Remove the Cancer

A Phase 3 Randomized, Double-blind, Multi-center Study of Adjuvant Nivolumab Versus Placebo in Subjects With High Risk Invasive Urothelial Carcinoma (CheckMate 274: CHECKpoint Pathway and nivoluMAb Clinical Trial Evaluation 274)

INTRODUCTION

  • Org Study ID: CA209-274
  • Secondary ID: 2014-003626-40
  • NTC ID: NCT02632409
  • Sponsor: Bristol-Myers Squibb

BRIEF SUMMARY


The purpose of this study is to determine the effectiveness and safety of Nivolumab compared
to placebo in participants who have undergone radical surgery for invasive urothelial cancer.


  • Overall Status
    Recruiting
  • Start Date
    February 11, 2016
  • Phase
    Phase 3
  • Study Type
    Interventional

PRIMARY OUTCOMES

Primary Outcome 1 - Measure: Disease free survival (DFS)

Primary Outcome 1 - Timeframe: Approximately 5 years after the first subject is randomized

CONDITION

  • Various Advanced Cancer

ELIGIBILITY

For more information regarding BMS clinical trial participation, please visit
www.BMSStudyConnect.com

Inclusion Criteria:

- Must have had invasive urothelial cancer at high risk of recurrence originating in the
bladder, ureter, or renal pelvis

- Must have had radical surgical resection (e.g. radical cystectomy), performed within
the last 120 days

- Must have disease free status as determined by imaging within 4 weeks of dosing

- Tumor tissue must be provided for biomarker analysis

- Patients who have not received prior neoadjuvant cisplatin chemotherapy must be
ineligible for or refuse cisplatin-based adjuvant chemotherapy

Exclusion Criteria:

- Partial bladder or partial kidney removal (eg, partial cystectomy or partial
nephrectomy)

- Secondary Treatment (eg, adjuvant systemic chemotherapy for bladder cancer) following
surgical removal of bladder cancer

- Subjects with active, known or suspected autoimmune disease

- Prior malignancy active within the previous 3 years except for locally curable cancers
that have been apparently cured

- Condition requiring systemic treatment with either corticosteroids or other
immunosuppressive medications within 14 day of study drug administration

- Positive test for hepatitis B virus surface antigen (HBV s Ag) or hepatitis C virus
ribonucleic acid (HCV antibody) indicating acute or chronic infection

Gender: All

Minimum Age: N/A

Maximum Age: 18 Years

Healthy Volunteers: No

OFFICIAL INFORMATION

Name: Bristol-Myers Squibb

Role: Study Director

Affiliation: Bristol-Myers Squibb

Overall Contact

Name: Bristol-Myers Squibb

Phone: N/A

Email: Clinical.Trials@bms.com

LOCATION

Facility Status Contact
Facility: Alaska Urological Institute dba Alaska Clinical Research Center
Anchorage, Alaska 99503
United States
Status: Recruiting Contact:
William Clark, Site 0015
907-276-1455
Facility: Arizona Oncology Associates
Tucson, Arizona 85711
United States
Status: Recruiting Contact:
Christopher Di Simone, Site 0179
520-269-3821
Facility: University Of California San Francisco-Fresno
Clovis, California 93611
United States
Status: Recruiting Contact:
Uzair Chaudhary, Site 0061
559-499-6636
Facility: University Of California - Davis
Sacramento, California 95817
United States
Status: Recruiting Contact:
Chong-Xian Pan, Site 0172
916-734-3691
Facility: Rocky Mountain Cancer Centers
Lakewood, Colorado 80228
United States
Status: Recruiting Contact:
Nauman Moazzam, Site 0178
303-285-5081
Facility: Loyola University Medical Center
Maywood, Illinois 60153
United States
Status: Recruiting Contact:
Elizabeth Henry, Site 0168
708-327-2237
Facility: Ft. Wayne Med Onco-Hema Inc
Fort Wayne, Indiana 46804
United States
Status: Recruiting Contact:
Sunil Babu, Site 0094
260-484-8830
Facility: Tulane University
New Orleans, Louisiana 70112
United States
Status: Recruiting Contact:
Brian Lewis, Site 0171
504-988-6542
Facility: Fairview Health Services
Burnsville, Minnesota 55337
United States
Status: Recruiting Contact:
Gautam Jha, Site 0051
952-836-3608
Facility: GU Research Network, LLC
Omaha, Nebraska 68130
United States
Status: Recruiting Contact:
Luke Nordquist, Site 0003
402-991-8468
Facility: New York Oncology Hematology, P.C.
Albany, New York 12208
United States
Status: Recruiting Contact:
David Shaffer, Site 0176
518-262-6696
Facility: Winthrop University Hospital
Mineola, New York 11501
United States
Status: Recruiting Contact:
Mary O'Keeffe, Site 0007
516-663-3115
Facility: Mount Sinai Medical Center
New York, New York 10029
United States
Status: Recruiting Contact:
Matthew Galsky, Site 0006
212-824-7372
Facility: Memorial Sloan Kettering Cancer Center
New York, New York 10065
United States
Status: Recruiting Contact:
Dean Bajorin, Site 0001
646-422-4333
Facility: University Of North Carolina
Chapel Hill, North Carolina 27599-7305
United States
Status: Recruiting Contact:
Matthew Milowsky, Site 0166
919-962-8489
Facility: Providence Portland Medical Center
Portland, Oregon 97213
United States
Status: Recruiting Contact:
Brendan Curti, Site 0044
503-215-3943
Facility: Oregon Health & Science University
Portland, Oregon 97239
United States
Status: Recruiting Contact:
Jeremy Cetnar, Site 0010
503-494-3618
Facility: Northwest Cancer Specialists, Pc
Tigard, Oregon 97223
United States
Status: Recruiting Contact:
Ian Schnadig, Site 0180
503-528-5002
Facility: Lehigh Valley Health Network
Allentown, Pennsylvania 18103
United States
Status: Recruiting Contact:
Suresh Nair, Site 0074
610-402-1642
Facility: Allegheny General Hospital
Pittsburgh, Pennsylvania 15212
United States
Status: Recruiting Contact:
Shifeng Mao, Site 0011
412-359-6452
Facility: University of Pittsburgh Cancer Institute Cancer Services
Pittsburgh, Pennsylvania 15232
United States
Status: Recruiting Contact:
Leonard Appleman, Site 0040
412-623-8962
Facility: Erlanger Oncology & Hematology - Univ. of TN
Chattanooga, Tennessee 37403
United States
Status: Recruiting Contact:
Robert Graham, Site 0009
423-778-2982
Facility: Virginia Oncology Associates
Virginia Beach, Virginia 23456
United States
Status: Recruiting Contact:
Mark Fleming, Site 0234
757-262-4633
Facility: COIBA
Berazategui, Buenos Aires 1880
Argentina
Status: Recruiting Contact:
Mirta Varela, Site 0021
+541143509606
Facility: Instituto Medico Especializado Alexander Fleming
Capital Federal, Buenos Aires 1426
Argentina
Status: Recruiting Contact:
Juan Sade, Site 0090
+541132218900
Facility: Hospital Italiano De Buenos Aires
Ciudad Autonoma De Buenos Aire, Buenos Aires 1181
Argentina
Status: Recruiting Contact:
Federico Cayol, Site 0089
+541149590200
Facility: Hospital Britanico De Buenos Aires
Ciudad Autonoma de BuenosAires, Buenos Aires C1280AEB
Argentina
Status: Recruiting Contact:
Ernesto Korbenfeld, Site 0022
541163819972
Facility: Clinica Viedma S.A.
Viedma, RIO Negro 8500
Argentina
Status: Recruiting Contact:
Ruben Kowalyszyn, Site 0102
+542920424417
Facility: Centro Para La Atencion Integral Del Paciente Oncologico
San Miguel De Tucuman, Tucuman 4000
Argentina
Status: Recruiting Contact:
Felipe Palazzo, Site 0020
+543814215825
Facility: Liverpool Hospital
Liverpool, New South Wales 2170
Australia
Status: Recruiting Contact:
Bavanthi Balakrishnar, Site 0048
+61287385234
Facility: Calvary Mater Newcastle
Waratah, New South Wales 2298
Australia
Status: Recruiting Contact:
Craig Gedye, Site 0046
+61240143282
Facility: Frankston Hospital
Frankston, Victoria 3199
Australia
Status: Recruiting Contact:
Emma Beardsley, Site 0184
+61397848562
Facility: St John of God Murdoch Hospital
Perth, Western Australia 6150
Australia
Status: Recruiting Contact:
Kynan Feeney, Site 0175
+61894288556
Facility: Lyell McEwin Hospital
Elizabeth Vale, 5112
Australia
Status: Recruiting Contact:
Christopher Hocking, Site 0050
+61882820833
Facility: Krankenhaus der Elisabethinen Linz GmbH
Linz, 4010
Austria
Status: Recruiting Contact:
Wolfgang Loidl, Site 0133

Facility: Salzburger Landeskliniken Lkh
Salzburg, 5020
Austria
Status: Recruiting Contact:
Daniela Colleselli, Site 0136

Facility: Akh Wien
Vienna, 1090
Austria
Status: Recruiting Contact:
Gottfried Locker, Site 0132

Facility: AKH Allgemeines Krankenhaus Wien
Wien, 1090
Austria
Status: Recruiting Contact:
Shahrokh Shariat, Site 0183

Facility: Local Institution
Hasselt, 3500
Belgium
Status: Recruiting Contact:
Site 0029

Facility: Chu De Liege
Liege, 4000
Belgium
Status: Recruiting Contact:
Christine Gennigens, Site 0027
+3243667664
Facility: Associacao Hospital de Caridade Ijui
Ijui, RIO Grande DO SUL 98700-000
Brazil
Status: Recruiting Contact:
Fabio Franke, Site 0071
+555533319393
Facility: Hospital Sao Lucas Da Pucrs
Porto Alegre, RIO Grande DO SUL 90610-000
Brazil
Status: Recruiting Contact:
Andre Fay, Site 0072
5133203236
Facility: Fundacao Pio Xii Hosp Cancer De Barretos
Barretos, SAO Paulo 14780-070
Brazil
Status: Recruiting Contact:
Joao Neif Junior, Site 0070
+551733216638
Facility: Local Institution
Cerqueira Cesar, SAO Paulo 01246-000
Brazil
Status: Recruiting Contact:
Site 0073

Facility: Ibcc - Inst. Bras. De Controle De Cancer
S?o Paulo, SAO Paulo 03102-006
Brazil
Status: Recruiting Contact:
Felipe Cruz, Site 0100
1134744222
Facility: Inca - Instituto Nacional Do Cancer
Rio De Janeiro, 20231-050
Brazil
Status: Recruiting Contact:
Alexander Dias, Site 0231
+552132076585
Facility: Local Institution
Edmonton, Alberta T6G 1Z2
Canada
Status: Recruiting Contact:
Site 0139

Facility: Mcgill University Health Center - Royal Victoria Hospital
Montreal, Quebec H4A 3J1
Canada
Status: Recruiting Contact:
Wassim Kassouf, Site 0109
514934193436686
Facility: Centre integre universitaire de sante et de service sociaux de l'estrie - CHUS
Sherbrooke, Quebec J1H 5N4
Canada
Status: Recruiting Contact:
Michel Pavic, Site 0112
819346111012811
Facility: Centre Hospitalier De L'Universite De Montreal
Montreal, H2X 0A9
Canada
Status: Recruiting Contact:
Fred Saad, Site 0101
514890800026161
Facility: Fundacion Arturo Lopez Perez
Santiago, Metropolitana
Chile
Status: Recruiting Contact:
Pamela Salman, Site 0099
+5624457254
Facility: Instituto Oncologico Clinica Renaca
Vina Del Mar, Valparaiso 2540364
Chile
Status: Recruiting Contact:
Pablo Gonzalez Mella, Site 0038
+56322891219
Facility: Clinica Alemana de Temuco S.A.
Temuco, 4810297
Chile
Status: Recruiting Contact:
Felipe Rey, Site 0137
56452201611
Facility: Local Institution
Beijing, Beijing 100001
China
Status: Recruiting Contact:
Site 0191

Facility: Local Institution
Beijing, Beijing 100034
China
Status: Recruiting Contact:
Site 0206

Facility: Local Institution
Beijing, Beijing 100050
China
Status: Recruiting Contact:
Site 0192

Facility: Local Institution
Chongqing, Chongqing 400030
China
Status: Recruiting Contact:
Site 0210

Facility: Local Institution
Fuzhou, Fujian 350001
China
Status: Recruiting Contact:
Site 0198

Facility: Local Institution
Guangzhou, Guangdong 510120
China
Status: Recruiting Contact:
Site 0222

Facility: Local Institution
Guangzhou, Guangdong 510288
China
Status: Recruiting Contact:
Site 0203

Facility: Local Institution
Nanning, Guangxi 530021
China
Status: Recruiting Contact:
Site 0227

Facility: Local Institution
Wuhan, Hubei 430030
China
Status: Recruiting Contact:
Site 0196

Facility: Local Institution
Nanjing, Jiangsu 210008
China
Status: Recruiting Contact:
Site 0220

Facility: Local Institution
Nanjing, Jiangsu 210029
China
Status: Recruiting Contact:
Site 0204

Facility: Local Institution
Nanchang, Jiangxi 330006
China
Status: Recruiting Contact:
Site 0223

Facility: Local Institution
Yantai, Shandong 264000
China
Status: Recruiting Contact:
Site 0212

Facility: Local Institution
Shanghai, Shanghai 200032
China
Status: Recruiting Contact:
Site 0193

Facility: Local Institution
Shanghai, Shanghai 200040
China
Status: Recruiting Contact:
Site 0199

Facility: Local Institution
Shanghai, Shanghai 200040
China
Status: Recruiting Contact:
Site 0217

Facility: Local Institution
Chengdu, Sichuan 610041
China
Status: Recruiting Contact:
Site 0229

Facility: Local Institution
Chengdu, Sichuan 610072
China
Status: Recruiting Contact:
Site 0219

Facility: Local Institution
Hangzhou, Zhejiang 310009
China
Status: Recruiting Contact:
Site 0221

Facility: Local Institution
Hangzhou, Zhejiang 310014
China
Status: Recruiting Contact:
Site 0195

Facility: Local Institution
Wenzhou, Zhejiang 325003
China
Status: Recruiting Contact:
Site 0230

Facility: Local Institution
Shanghai, 200032
China
Status: Recruiting Contact:
Site 0202

Facility: Administradora Del Country S.A. - Clinica Del Country
Bogota,
Colombia
Status: Recruiting Contact:
Andres Felipe Cardona Zorrilla, Site 0092
57153004702907
Facility: Fundacion Oftalmologica De Santander - Foscal
Floridablanca,
Colombia
Status: Recruiting Contact:
Milton Salazar, Site 0093
57767979796161
Facility: Hospital Pablo Tobon Uribe
Medellin, MEDELLIN
Colombia
Status: Recruiting Contact:
Jose Correa, Site 0091
5744459753
Facility: Local Institution
Aalborg, 9100
Denmark
Status: Recruiting Contact:
Site 0108

Facility: Local Institution
Aarhus N, 8200
Denmark
Status: Recruiting Contact:
Site 0106

Facility: Local Institution
Copenhagen, 2100
Denmark
Status: Recruiting Contact:
Site 0107

Facility: Local Institution
Clermont-ferrand, 63000
France
Status: Recruiting Contact:
Site 0233

Facility: Local Institution
La Roche sur Yon, 85320
France
Status: Recruiting Contact:
Site 0115

Facility: Local Institution
Marseille Cedex 9, 13273
France
Status: Recruiting Contact:
Site 0080

Facility: Local Institution
Paris, 75475
France
Status: Recruiting Contact:
Site 0081

Facility: Local Institution
Strasbourg, 67091
France
Status: Recruiting Contact:
Site 0113

Facility: Local Institution
Suresnes, 92151
France
Status: Recruiting Contact:
Site 0097

Facility: Zeisigwaldkliniken Bethanien
Chemnitz, 09130
Germany
Status: Recruiting Contact:
Hanjo Belz, Site 0131
+493714301730
Facility: Klinik Essen-Mitte
Essen, 45136
Germany
Status: Recruiting Contact:
Susanne Krege, Site 0125
+4920117424523
Facility: Univ Klinikum Der Ernst-Moritz-Arndt-Univ Greifswald
Greifswald, 17475
Germany
Status: Recruiting Contact:
Uwe Zimmermann, Site 0127
+493834865961
Facility: Uni Hamburg-Eppendorf
Hamburg, 20246
Germany
Status: Recruiting Contact:
Gunhild von Amsberg, Site 0126
+4940741053994
Facility: Local Institution
Heidelberg, 69120
Germany
Status: Recruiting Contact:
Site 0124

Facility: Universitaetsklinikum Jena
Jena, 07747
Germany
Status: Recruiting Contact:
Marc-Oliver Grimm, Site 0123
+4936419329956
Facility: Universitatsklinikum Giessen Und Marburg
Marburg, 35043
Germany
Status: Recruiting Contact:
Axel Hegele, Site 0188
+4964215863695
Facility: Universitaetsklinikum Muenster
Muenster, 48149
Germany
Status: Recruiting Contact:
Martin Boegemann, Site 0128
+492518349161
Facility: Klinikum rechts der Isar der Technischen Universitat Munchen
Munich, 81675
Germany
Status: Recruiting Contact:
Juergen Gschwend, Site 0122
+498941409858
Facility: Local Institution
Nuernberg, 90419
Germany
Status: Recruiting Contact:
Site 0185

Facility: Klinikum Stuttgart
Stuttgart, 70174
Germany
Status: Recruiting Contact:
Jan Schleicher, Site 0129
+4971127830411
Facility: Alexandra General Hospital
Athens, 11528
Greece
Status: Recruiting Contact:
Aristotelis Bamias, Site 0110
+302103381543
Facility: Theagenio Hospital
Thessaloniki, 54007
Greece
Status: Recruiting Contact:
Charalambos Andreadis, Site 0111
+302310898721
Facility: Local Institution
Wilton, Cork
Ireland
Status: Recruiting Contact:
Site 0054

Facility: Adelaide And Meath Hospital
Dublin,
Ireland
Status: Recruiting Contact:
Ray Mcdermott, Site 0052
+35314142012
Facility: Local Institution
Haifa, 3109601
Israel
Status: Recruiting Contact:
Site 0118

Facility: Local Institution
Jerusalem, 91120
Israel
Status: Recruiting Contact:
Site 0121

Facility: Local Institution
Ramat Gan, 5262100
Israel
Status: Recruiting Contact:
Site 0120

Facility: Local Institution
Zerifin, 70300
Israel
Status: Recruiting Contact:
Site 0119

Facility: Ospedale S. Donato - Usl 8
Arezzo, 52100
Italy
Status: Recruiting Contact:
Alketa Hamzaj, Site 0088
+3905752551 0000 0000
Facility: ASST Papa Giovanni XXIII
Bergamo, 24127
Italy
Status: Recruiting Contact:
Caterina Messina, Site 0197
+39035267111 000.000 000
Facility: IRCCS Istituto Nazionale Tumori Milano
Milano, 20133
Italy
Status: Recruiting Contact:
Andrea Necchi, Site 0082
+390223901 00 00000
Facility: Azienda Ospedaliera Universitaria Pisana
Pisa, 56126
Italy
Status: Recruiting Contact:
Luca Galli, Site 0084
+39050992111 000.000000
Facility: Arcispedale S. Maria Nuova - A.O. Reggio Emilia
Reggio Emilia, 42100
Italy
Status: Recruiting Contact:
Cristina Masini, Site 0189
+390522335111 0000.000000
Facility: Istituto Regina Elena
Roma, 00144
Italy
Status: Recruiting Contact:
Francesco Cognetti, Site 0085
+390652661 00 00000
Facility: AOUS - Policlinico S.Maria Alle Scotte
Siena, 53100
Italy
Status: Recruiting Contact:
Michele Maio, Site 0083
+390577585111 0000 000000
Facility: Local Institution
Akita-shi, Akita 0108543
Japan
Status: Recruiting Contact:
Site 0142

Facility: Local Institution
Hirosaki-shi, Aomori 036-8563
Japan
Status: Recruiting Contact:
Site 0144

Facility: Local Institution
Chiba-shi, Chiba 260-8717
Japan
Status: Recruiting Contact:
Site 0143

Facility: Local Institution
Fukuoka-shi, Fukuoka 8128582
Japan
Status: Recruiting Contact:
Site 0162

Facility: Local Institution
Sapporo-shi, Hokai-do 060-8543
Japan
Status: Recruiting Contact:
Site 0160

Facility: Local Institution
Sapporo-shi, Hokkaido 0608648
Japan
Status: Recruiting Contact:
Site 0161

Facility: Local Institution
Tsukuba-shi, Ibaraki 3058576
Japan
Status: Recruiting Contact:
Site 0148

Facility: Local Institution
Nagasaki-shi, Nagasaki 8528501
Japan
Status: Recruiting Contact:
Site 0163

Facility: Local Institution
Niigata-shi, Niigata 9518520
Japan
Status: Recruiting Contact:
Site 0150

Facility: Local Institution
Okayama-shi, Okayama 7000914
Japan
Status: Recruiting Contact:
Site 0141

Facility: Local Institution
Higashinari-ku, Osaka 5378511
Japan
Status: Recruiting Contact:
Site 0164

Facility: Local Institution
Osaka-Sayama-Shi, Osaka 5898511
Japan
Status: Recruiting Contact:
Site 0149

Facility: Local Institution
Hamamatsu-shi, Shizuoka 4313192
Japan
Status: Recruiting Contact:
Site 0151

Facility: Local Institution
Bunkyo-ku, Tokyo 113-8603
Japan
Status: Recruiting Contact:
Site 0146

Facility: Local Institution
Shinjuku-Ku, Tokyo 1608582
Japan
Status: Recruiting Contact:
Site 0145

Facility: Local Institution
Shinjuku-ku, Tokyo 1628666
Japan
Status: Recruiting Contact:
Site 0147

Facility: Local Institution
Seongnam-si, Gyeonggi-do 13620
Korea, Republic of
Status: Recruiting Contact:
Site 0155

Facility: Local Institution
Seoul, 03722
Korea, Republic of
Status: Recruiting Contact:
Site 0154

Facility: Local Institution
Seoul, 05505
Korea, Republic of
Status: Recruiting Contact:
Site 0152

Facility: Local Institution
Seoul, 06351
Korea, Republic of
Status: Recruiting Contact:
Site 0156

Facility: Local Institution
Df, Distrito Federal 06720
Mexico
Status: Recruiting Contact:
Site 0138

Facility: Arke Estudios Clinicos Sa De Cv
Mexico, Distrito Federal 06700
Mexico
Status: Recruiting Contact:
Manuel Magallanes, Site 0116
5554137773
Facility: Local Institution
Mexico, Distrito Federal 14080
Mexico
Status: Recruiting Contact:
Site 0039

Facility: Local Institution
Guadalajara, Jalisco 44270
Mexico
Status: Recruiting Contact:
Site 0035

Facility: Hospital Universitario Dr. Jose Eleuterio Gonzalez
Monterrey, Nuevo LEON 64460
Mexico
Status: Recruiting Contact:
Yamil-Alonso Lopez Chuken, Site 0032
8115443345
Facility: Local Institution
Amsterdam, 1105 AZ
Netherlands
Status: Recruiting Contact:
Site 0069

Facility: Local Institution
Maastrict, 6229 HX
Netherlands
Status: Recruiting Contact:
Site 0068

Facility: Local Institution
Nijmegen, 6525 GA
Netherlands
Status: Recruiting Contact:
Site 0041

Facility: Clinica Internacional sede San Borja
Lima, Lima 41
Peru
Status: Recruiting Contact:
Renzo Salas, Site 0043

Facility: Klinika Onkologii i Radioterapii
Gdansk, 80-952
Poland
Status: Recruiting Contact:
Elzbieta Senkus-Konefka, Site 0055
+48583492214
Facility: Oddzial Onkologii Klinicznej
Wroclaw, 53-413
Poland
Status: Recruiting Contact:
Krzysztof Tupikowski, Site 0186
+48713689677
Facility: Local Institution
Bucuresti, 021389
Romania
Status: Recruiting Contact:
Site 0182

Facility: Local Institution
Craiova, 200347
Romania
Status: Recruiting Contact:
Site 0096

Facility: Local Institution
Floresti, 407280
Romania
Status: Recruiting Contact:
Site 0078

Facility: Local Institution
Timisoara, Timis, 300239
Romania
Status: Recruiting Contact:
Site 0181

Facility: Local Institution
Moscow, 125284
Russian Federation
Status: Recruiting Contact:
Site 0140

Facility: Local Institution
Saint-Petersburg, 197758
Russian Federation
Status: Recruiting Contact:
Site 0031

Facility: Hospital Universitari Germans Trias I Pujol
Badalona-barcelona, 08916
Spain
Status: Recruiting Contact:
Olatz Etxaniz, Site 0067
+34934978729
Facility: Hospital General Universitari Vall D'Hebron
Barcelona, 08035
Spain
Status: Recruiting Contact:
Rafael Morales, Site 0066
+34932746000
Facility: Hospital General Universitario Gregorio Maranon
Madrid, 28007
Spain
Status: Recruiting Contact:
Jose Angel Arranz, Site 0064
+34915868115
Facility: Hospital Ramon Y Cajal
Madrid, 28034
Spain
Status: Recruiting Contact:
Pablo Gajate, Site 0062
+34913368263
Facility: Hosp Univer 12 De Octubre
Madrid, 28041
Spain
Status: Recruiting Contact:
Daniel Castellano, Site 0063
+34913908339
Facility: H. U. Marques de Valdecilla
Santander, 39008
Spain
Status: Recruiting Contact:
Ignacio Duran, Site 0232
+34942315004
Facility: Hosp. Univ. Virgen Del Rocio
Sevilla, 41013
Spain
Status: Recruiting Contact:
Begona Perez Valderrama, Site 0065
+34955011368
Facility: Local Institution
Lund, 221 85
Sweden
Status: Recruiting Contact:
Site 0105

Facility: Kantonsspital Basel
Basel, 4031
Switzerland
Status: Recruiting Contact:
Frank Stenner, Site 0134
+41613287538
Facility: OnkoZentrum Zurich
Zuerich, 8038
Switzerland
Status: Recruiting Contact:
Ulf Petrausch, Site 0135

Facility: Local Institution
Kaohsiung, 80765
Taiwan
Status: Recruiting Contact:
Site 0158

Facility: Local Institution
Taichung, 404
Taiwan
Status: Recruiting Contact:
Site 0159

Facility: Local Institution
Taipei, 100
Taiwan
Status: Recruiting Contact:
Site 0153

Facility: Local Institution
London, Greater London SE1 9RT
United Kingdom
Status: Recruiting Contact:
Site 0036

Facility: Local Institution
Manchester, Greater Manchester M20 4BX
United Kingdom
Status: Recruiting Contact:
Site 0025

Facility: Local Institution
Edinburgh, Midlothian EH4 2XU
United Kingdom
Status: Recruiting Contact:
Site 0076

Facility: Local Institution
Sutton, Surrey SM2 5PT
United Kingdom
Status: Recruiting Contact:
Site 0024

Facility: Cancer Research Centre
Sheffield, Yorkshire S10 2SJ
United Kingdom
Status: Recruiting Contact:
Linda Evans, Site 0059
+441142265000
Facility: Local Institution
London, SW3 6JJ
United Kingdom
Status: Recruiting Contact:
Site 0114