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Brief Title: Neoadjuvant Chemotherapy Alone Versus Neoadjuvant Chemotherapy Plus Nivolumab or Nivolumab and BMS-986205, Followed by Continued Post- Surgery Therapy With Nivolumab or Nivolumab and BMS-986205 in Participants With Muscle- Invasive Bladder Cancer

A Phase 3, Randomized, Study of Neoadjuvant Chemotherapy Alone Versus Neoadjuvant Chemotherapy Plus Nivolumab or Nivolumab and BMS-986205, Followed by Continued Post- Surgery Therapy With Nivolumab or Nivolumab and BMS-986205 in Participants With Muscle- Invasive Bladder Cancer

INTRODUCTION

  • Org Study ID: CA017-078
  • Secondary ID: 2017-004692-31
  • NTC ID: NCT03661320
  • Sponsor: Bristol-Myers Squibb
BMS Clinical Trial Information, BMS Clinical Trial Patient Recruiting, FDA Safety Alerts and Recalls

DESCRIPTION

Who is this trial for?

Patients with muscle-invasive bladder cancer who are eligible for radical cystectomy

What is the goal of this study?

To study the effects of the combination of drugs over time in patients who remain free of disease complications (EFS) and overall survival.

Summary

A phase 3, research study to evaluate nivolumab + chemotherapy or nivolumab/ BMS-986205 + chemotherapy followed by continued Immuno-Oncology therapy after radical cystectomy (RC) compared with neoadjuvant standard of care (SOC) chemotherapy alone in patients with muscle-invasive bladder cancer.

Background

MIBC patients have a 50% 5 year survival rate after radical cystectomy surgery (surgery to remove bladder and nearby tissue) and a return of cancer rate, 30-54%. 1.  Therefore, additional treatment before and/or after surgery is often considered to lower the chance that the cancer returns.  Clinical studies are research tests of an investigational drug or drugs in people.  A drug must be tested in clinical studies before it may be used for patients in the general public.

You may be eligible for this clinical study if you:

Have muscle -invasive bladder cancer, cancer that has spread to the muscle wall of the bladder

Plan to have a radical cystectomy surgery, surgery to remove bladder and nearby tissue

Do not have an autoimmune disease

Are eligible for cisplatin treatment

Participation in this clinical trial is determined using the full eligibility criteria. Some key eligibility criteria are above. To prescreen for this study or other bladder cancer studies, please take the Bladder Cancer Screener on BMS Study Connect.

Gender: All          Minimum Age: 18 Years          Maximum Age: N/A

Study Design

Patients enrolled in the trial will be randomly assigned to one of the following study treatment arms

  1. pre-surgery chemotherapy followed by surgery then standard of care observation
  2. pre-surgery chemotherapy plus Nivolumab followed by surgery then chemotherapy and Nivolumab
  3. pre-surgery chemotherapy plus Nivolumab and investigational drug followed by surgery then chemotherapy and Nivolumab and investigational drug

Considering a clinical trial?

There is a lot to think about when considering a clinical trial.

Download this pdf to discuss 2 clinical trial options with your doctor.

Visit BMSSTUDYCONNECT.com/ to learn move and to take a screener to see if you qualify for this or other trials.

BRIEF SUMMARY

The purpose of this study is to compare nivolumab plus neoadjuvant gemcitabine/cisplatin (GC) chemotherapy, followed by post-surgery continuation of immuno-oncology (IO) therapy, with neoadjuvant GC chemotherapy alone in adult participants with previously untreated muscle-invasive bladder cancer (MIBC).

  • Overall Status
    Recruiting
  • Start Date
    November 6, 2018
  • Phase
    Phase 3
  • Study Type
    Interventional

PRIMARY OUTCOMES

Primary Outcome 1 - Measure: Pathological Complete Response (pCR) rate, in all randomized participants

Primary Outcome 1 - Timeframe: Approximately 43 months

Primary Outcome 2 - Measure: Event-Free Survival (EFS), in all randomized participants

Primary Outcome 2 - Timeframe: Approximately 51 months

CONDITION

  • Urinary Bladder Neoplasms
  • Muscle-Invasive Bladder Cancer

ELIGIBILITY

Inclusion Criteria:
Participant must be deemed eligible for Radial Cystectomy (RC) by his/her oncologist and/or urologist, and must agree to undergo Radial Cystectomy (RC) after completion of neoadjuvant therapy.

- Eastern Cooperative Oncology Group (ECOG) Performance Status 0 or 1
Exclusion Criteria:
Clinical evidence of positive lymph node(s) (LN) (≥ 10 mm in short axis) or metastatic bladder cancer

- Prior systemic therapy, radiation therapy, or surgery for bladder cancer other than trans urethral resection of bladder tumor (TURBT) or biopsies is also not permitted

Gender: All

Minimum Age: 18 Years

Maximum Age: N/A

Healthy Volunteers: No

OFFICIAL INFORMATION

Name: Bristol-Myers Squibb

Role: Study Director

Affiliation: Bristol-Myers Squibb

Overall Contact

Name: Bristol-Myers Squibb

Phone: 855-907-3286

Email: Clinical.Trials@bms.com

LOCATION

Facility Status Contact
Facility: Arizona Oncology Associates
Tucson, Arizona 85711
United States
Status: Recruiting Contact: Contact
Rami Owera, Site 0036
850-696-4423
Facility: Rocky Mountain Cancer Centers Llp
Littleton, Colorado 80120-4413
United States
Status: Recruiting Contact: Contact
Guru Sonpavde, Site 0166
617975742857428
Facility: Woodlands Medical Specialists, Pa
Pensacola, Florida 32503
United States
Status: Recruiting Contact: Contact
Samith Kochuparambil, Site 0025
612-884-6363
Facility: Northside Hospital
Atlanta, Georgia 30342
United States
Status: Recruiting Contact: Contact
Benjamin Teply, Site 0001
402-559-8649
Facility: The University Of Chicago
Chicago, Illinois 60637
United States
Status: Recruiting Contact: Contact
Oscar Goodman, Site 0024
757-262-4633
Facility: Illinois Cancer Care
Peoria, Illinois 61615
United States
Status: Recruiting Contact: Contact
David Shaffer, Site 0029
518-489-3612
Facility: Maryland Oncology Hematology, P.A.
Columbia, Maryland 21044
United States
Status: Recruiting Contact: Contact
Shilpa Gupta, Site 0191
612-624-5620
Facility: Beth Israel Deaconess Medical Center
Boston, Massachusetts 02215
United States
Status: Recruiting Contact: Contact
Ian Schnadig, Site 0028
971-708-8700
Facility: Cancer Center At Milford Regional Medical Center
Boston, Massachusetts 02215
United States
Status: Recruiting Contact: Contact
Theodore Gourdin, Site 0189
843-792-9007
Facility: Dana Farber Cancer Institute
Boston, Massachusetts 02215
United States
Status: Recruiting Contact: Contact
Nancy Davis, Site 0007
615-936-8422
Facility: Minnesota Oncology Hematology
Minneapolis, Minnesota 55404
United States
Status: Recruiting Contact: Contact
Jeffrey Yorio, Site 0030
512-427-9400
Facility: Oncology Hematology West P.C. dba Nebraska Cancer Specialists
Omaha, Nebraska 68130
United States
Status: Recruiting Contact: Contact
Site 0051
+5411482770003228
Facility: University Of Nebraska Medical Center
Omaha, Nebraska 68198-6840
United States
Status: Recruiting Contact: Contact
Site 0049
+61298123538
Facility: Comprehensive Cancer Centers Of Nevada
Las Vegas, Nevada 89169
United States
Status: Recruiting Contact: Contact
Gabriela Gatica, Site 0151
+61882399536
Facility: New York Oncology Hematology, Pc
Albany, New York 12208
United States
Status: Recruiting Contact: Contact
Site 0130
+435125042333
Facility: Columbia University Medical Center (Cumc)
New York, New York 10032
United States
Status: Recruiting Contact: Contact
Site 0043
+4314040054780
Facility: Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio 44195
United States
Status: Recruiting Contact: Contact
Rohit Joshi, Site 0143
+5585992819557
Facility: Northwest Cancer Specialists, Pc
Tigard, Oregon 97223
United States
Status: Recruiting Contact: Contact
Andrew Weickhardt, Site 0037
+553138012406
Facility: Medical University Of South Carolina
Charleston, South Carolina 29425
United States
Status: Recruiting Contact: Contact
Site 0038
+555533319393
Facility: Vanderbilt University Medical Center
Nashville, Tennessee 37232
United States
Status: Recruiting Contact: Contact
Wolfgang Eisterer, Site 0090
+551733216637
Facility: Texas Oncology-Central Austin Cancer Center
Austin, Texas 78731
United States
Status: Recruiting Contact: Contact
Site 0091
+551436021397
Facility: Virginia Oncology Associates
Norfolk, Virginia 23502
United States
Status: Recruiting Contact: Contact
Site 0060
+551122713482
Facility: Local Institution - 0051
Capital Federal, Buenos Aires 1426
Argentina
Status: Recruiting Contact: Contact
Site 0063
+56988039180
Facility: Local Institution - 0049
Ciudad Autónoma de Buenos Aires, Buenos Aires 1280
Argentina
Status: Recruiting Contact: Contact
Site 0062
573102020254
Facility: Hospital Aleman
Ciudad Autonoma Buenos Aires, Distrito Federal 1118
Argentina
Status: Recruiting Contact: Contact
Karine da Trindade, Site 0094
33322455499
Facility: Local Institution
Garran, Australian Capital Territory 2605
Australia
Status: Recruiting Contact: Contact
Luciano Viana, Site 0099
33241356494
Facility: Local Institution
Kingswood, New South Wales 2747
Australia
Status: Recruiting Contact: Contact
Fabio Franke, Site 0092
33556333333
Facility: Macquarie University
Macquarie University, New South Wales 2109
Australia
Status: Recruiting Contact: Contact
Site 0212
33473278186
Facility: Local Institution - 0043
St Leonards, New South Wales 2065
Australia
Status: Recruiting Contact: Contact
Site 0097
33496196234
Facility: Calvary Hospital
North Adelaide, South Australia 5006
Australia
Status: Recruiting Contact: Contact
Joao Antonio Junior, Site 0098
+492418088017
Facility: Austin Hospital
Heidelberg, Victoria 3084
Australia
Status: Recruiting Contact: Contact
Patricia Beato, Site 0095
+493617812201
Facility: Local Institution - 0038
Murdoch, Western Australia 6150
Australia
Status: Recruiting Contact: Contact
Gustavo Girotto, Site 0093
+4920117429073
Facility: Klinikum Klagenfurt Am Woerthersee
Klagenfurt Am Woerthersee, Ceara 9020
Austria
Status: Recruiting Contact: Contact
Victor Marcondes Lopes dos Santos, Site 0164
+4969630184778
Facility: Local Institution - 0091
Krems, Minas Gerais 3500
Austria
Status: Recruiting Contact: Contact
Brigitte Adam Van Eyll, Site 0214
+49551398656
Facility: Krankenhaus der Elisabethinen Linz GmbH
Linz, RIO Grande DO SUL 4010
Austria
Status: Recruiting Contact: Contact
Site 0159
+4923234995252
Facility: AKH Allgemeines Krankenhaus Wien
Wien, RIO Grande DO SUL 1090
Austria
Status: Recruiting Contact: Contact
Site 0182
+4945150043699
Facility: Local Institution
Bruxelles, RIO Grande DO SUL 1200
Belgium
Status: Recruiting Contact: Contact
Site 0192
+493916715036
Facility: Local Institution - 0063
Gent, Sao Paulo 9000
Belgium
Status: Recruiting Contact: Contact
Site 0190
+496131172301
Facility: Local Institution
Wilrijk, Sao Paulo 2610
Belgium
Status: Recruiting Contact: Contact
Site 0052
+496512081921
Facility: Oncocentro Servico Medicos e Hospitalares Ltda
Fortaleza, British Columbia 60130-241
Brazil
Status: Recruiting Contact: Contact
Site 0210
+306974307206
Facility: Hospital Marcio Cunha
Ipatinga, British Columbia 35160-158
Brazil
Status: Recruiting Contact: Contact
Site 0054
+390805555355
Facility: ONCOSITE - Centro de Pesquisa Clinica em Oncologia
Ijui, Ontario 98700-000
Brazil
Status: Recruiting Contact: Contact
Site 0201
+39059659981
Facility: Local Institution - 0212
Porto Alegre, Quebec 90035-001
Brazil
Status: Recruiting Contact: Contact
Nicolas Villarreal, Site 0104

Facility: Local Institution - 0097
Porto Alegre, Quebec 90610000
Brazil
Status: Recruiting Contact: Contact
Site 0103

Facility: Fundacao Pio Xii Hosp Cancer De Barretos
Barretos, Metropolitana 14780-070
Brazil
Status: Recruiting Contact: Contact
Site 0148

Facility: Fundacao Doutor Amaral Carvalho
Jau, Metropolitana 17210-080
Brazil
Status: Recruiting Contact: Contact
Site 0145

Facility: Hospital De Base Da Faculdade De Medicina De Rio Preto
Sao Jose Do Rio Preto, Metropolitana 15090-000
Brazil
Status: Recruiting Contact: Contact
Site 0146

Facility: Inca - Instituto Nacional Do Cancer
Rio De Janeiro, Metropolitana 20231-050
Brazil
Status: Recruiting Contact: Contact
Site 0202

Facility: Instituto do Cancer Arnaldo Vieira de Carvalho
Sao Paulo, Bogota 01221-020
Brazil
Status: Recruiting Contact: Contact
Site 0204

Facility: Local Institution
Kelowna, Thessalía V1Y 5L3
Canada
Status: Recruiting Contact: Contact
Site 0101

Facility: Local Institution - 0182
North York, Tel-Aviv M2K 1E1
Canada
Status: Recruiting Contact: Contact
Guilhem Roubaud, Site 0217

Facility: Local Institution
Chicoutimi, Aichi G7H 5H6
Canada
Status: Recruiting Contact: Contact
Hakim Mahammedi, Site 0199

Facility: Local Institution
Montreal, Hokkaido H3T 1M5
Canada
Status: Recruiting Contact: Contact
Site 0206

Facility: Pontificia Universidad Catolica de Chile
Santiago, Hokkaido 8330024
Chile
Status: Recruiting Contact: Contact
Jean-Baptiste Paoli, Site 0075

Facility: Local Institution - 0052
Santiago, Hokkaido 8380456
Chile
Status: Recruiting Contact: Contact
Site 0200

Facility: Local Institution - 0210
Santiago, Ibaraki 8420383
Chile
Status: Recruiting Contact: Contact
Site 0074

Facility: Local Institution - 0054
Santiago, Kagawa 0
Chile
Status: Recruiting Contact: Contact
Site 0163

Facility: Local Institution - 0201
Colombia, Kanagawa 681004
Colombia
Status: Recruiting Contact: Contact
Site 0020

Facility: Foscal Internacional
Bucaramanga, Niigata 230003
Colombia
Status: Recruiting Contact: Contact
Site 0188

Facility: Local Institution - 0103
Monteria, Osaka 9000
Colombia
Status: Recruiting Contact: Contact
Site 0002

Facility: Local Institution
Helsinki, Tokyo 33521
Finland
Status: Recruiting Contact: Contact
Susanne Krege, Site 0081

Facility: Local Institution
Tampere, Tokyo 20251
Finland
Status: Recruiting Contact: Contact
Severine Banek, Site 0086

Facility: Local Institution
Turku, Gyeonggi-do 29609
Finland
Status: Recruiting Contact: Contact
Arne Strauss, Site 0080

Facility: Local Institution - 0202
Brest, Gyeonggi-do 94010
France
Status: Recruiting Contact: Contact
Florian Roghmann, Site 0013

Facility: Local Institution - 0204
Créteil, BAJA Californa SUR 80054
France
Status: Recruiting Contact: Contact
Site 0010

Facility: CHU Amiens - Picardie
Amiens, Distrito Federal 49100
France
Status: Recruiting Contact: Contact
Mario Kramer, Site 0084

Facility: Chu Angers
Angers, Jalisco 25030
France
Status: Recruiting Contact: Contact
Martin Schostak, Site 0079

Facility: Local Institution - 0101
Besancon Cedex, Nuevo LEON 33075
France
Status: Recruiting Contact: Contact
Igor Tsaur, Site 0100

Facility: Institut Bergonie
Bordeaux, Yorkshire 63000
France
Status: Recruiting Contact: Contact
Clemens Huettenbrink, Site 0016

Facility: Centre Jean Perrin
Clermont-ferrand, 38043
France
Status: Recruiting Contact: Contact
Andreas Neisius, Site 0085

Facility: Local Institution - 0206
La Tronche, 13273
France
Status: Recruiting Contact: Contact
Site 0031

Facility: Hopital Prive CLAIRVAL
Marseille, 34298
France
Status: Recruiting Contact: Contact
Site 0194

Facility: Local Institution - 0200
Montpellier Cedex 5, 06189
France
Status: Recruiting Contact: Contact
Evangelos Bournakis, Site 0195

Facility: Local Institution - 0074
Nice, 75014
France
Status: Recruiting Contact: Contact
Site 0196

Facility: Local Institution - 0163
Paris, 69495
France
Status: Recruiting Contact: Contact
Site 0068

Facility: Local Institution - 0020
Pierre Benite Cedax, 35042
France
Status: Recruiting Contact: Contact
Site 0066

Facility: Local Institution - 0188
Saint Herblain Cedex, 67091
France
Status: Recruiting Contact: Contact
Emanuele Naglieri, Site 0064

Facility: Local Institution - 0002
Strasbourg Cedex, 31059
France
Status: Recruiting Contact: Contact
Site 0193

Facility: Local Institution - 0003
TOULOUSE Cedex 9, 52074
France
Status: Recruiting Contact: Contact
Site 0032

Facility: Universitaetsklinikum Aachen
Aachen, 99028
Germany
Status: Recruiting Contact: Contact
Claudia Mucciarini, Site 0065

Facility: Helios Klinikum Erfurt
Erfurt, 45136
Germany
Status: Recruiting Contact: Contact
Site 0033

Facility: Klinik Essen-Mitte
Essen, 60590
Germany
Status: Recruiting Contact: Contact
Site 0034

Facility: Johann Wolfgang Goethe Universitaet
Frankfurt Main, 37075
Germany
Status: Recruiting Contact: Contact
Site 0035

Facility: Universitaetsmedizin Goettingen
Goettingen, 69120
Germany
Status: Recruiting Contact: Contact
Site 0186

Facility: Marien Hospital Herne
Herne, 07747
Germany
Status: Recruiting Contact: Contact
Site 0177

Facility: Local Institution - 0010
Jena, 23538
Germany
Status: Recruiting Contact: Contact
Site 0185

Facility: University Hospital Schleswig-Holstein
Luebeck, 39120
Germany
Status: Recruiting Contact: Contact
Site 0179

Facility: Universitaetsklinikum Magdeburg
Magdeburg, 55101
Germany
Status: Recruiting Contact: Contact
Site 0171

Facility: Universitaetsmedizin Der Johannes Gutenberg-Universitaet
Mainz, 81675
Germany
Status: Recruiting Contact: Contact
Site 0169

Facility: Local Institution - 0082
Muenchen, 90419
Germany
Status: Recruiting Contact: Contact
Site 0168

Facility: Klinikum Nuernberg Nord, Urologische Klinik
Nuernberg, 54292
Germany
Status: Recruiting Contact: Contact
Site 0173

Facility: Krankenhaus der Barmherzigen Brueder
Trier, 411 10
Germany
Status: Recruiting Contact: Contact
Site 0175

Facility: Local Institution - 0031
Larissa, 11528
Greece
Status: Recruiting Contact: Contact
Site 0176

Facility: Local Institution - 0194
Chaidari, 15562
Greece
Status: Recruiting Contact: Contact
Site 0178

Facility: Metropolitan General Hospital
Holargos, 6423906
Greece
Status: Recruiting Contact: Contact
Site 0172

Facility: Local Institution - 0196
Tel Aviv, 84101
Israel
Status: Recruiting Contact: Contact
Site 0174

Facility: Local Institution
Beer Sheva, 3109601
Israel
Status: Recruiting Contact: Contact
Site 0180

Facility: Local Institution
Haifa, 52621
Israel
Status: Recruiting Contact: Contact
Site 0137

Facility: Local Institution
Ramat Gan, 70124
Israel
Status: Recruiting Contact: Contact
Site 0203

Facility: IRCCS Giovanni Paolo II Istituto Oncologico
Bari, 47014
Italy
Status: Recruiting Contact: Contact
Site 0220

Facility: Local Institution - 0193
Forlì, 20133
Italy
Status: Recruiting Contact: Contact
Site 0218

Facility: Local Institution - 0032
Milano, 41012
Italy
Status: Recruiting Contact: Contact
Site 0208

Facility: Ospedale Di Carpi
Modena, 35128
Italy
Status: Recruiting Contact: Contact
Site 0215

Facility: Local Institution - 0033
Padova, 56126
Italy
Status: Recruiting Contact: Contact
Site 0140

Facility: Local Institution - 0034
Pisa, 00168
Italy
Status: Recruiting Contact: Contact
Site 0136

Facility: Local Institution - 0035
Roma, 485-8520
Italy
Status: Recruiting Contact: Contact
Site 0211

Facility: Local Institution - 0186
Komaki, 0030804
Japan
Status: Recruiting Contact: Contact
Site 0138

Facility: Local Institution
Sapporo, 060-8543
Japan
Status: Recruiting Contact: Contact
Site 0160

Facility: Local Institution - 0177
Sapporo, 0608604
Japan
Status: Recruiting Contact: Contact
Site 0161

Facility: Local Institution
Sapporo, 3058576
Japan
Status: Recruiting Contact: Contact
Site 0056

Facility: Local Institution
Tsukuba-shi, 761-0793
Japan
Status: Recruiting Contact: Contact
Site 0105

Facility: Local Institution - 0171
Kita-gun, 222-0036
Japan
Status: Recruiting Contact: Contact
Site 0070

Facility: Local Institution
Yokohama, 9518520
Japan
Status: Recruiting Contact: Contact
Site 0072

Facility: Local Institution
Niigata-shi, 589-8511
Japan
Status: Recruiting Contact: Contact
Site 0073

Facility: Local Institution
Osakasayama, 5698686
Japan
Status: Recruiting Contact: Contact
Site 0087

Facility: Local Institution
Takatsuki City, 3501298
Japan
Status: Recruiting Contact: Contact
Site 0089

Facility: Local Institution
Hidaka-shi, 4313192
Japan
Status: Recruiting Contact: Contact
Site 0158

Facility: Local Institution - 0170
Hamamatsu-shi, 1058470
Japan
Status: Recruiting Contact: Contact
Site 0132

Facility: Local Institution
Minato-ku, 160-8582
Japan
Status: Recruiting Contact: Contact
Site 0133

Facility: Local Institution
Shinjuku-ku, 812-8582
Japan
Status: Recruiting Contact: Contact
Site 0153

Facility: Local Institution - 0174
Fukuoka, 606-8507
Japan
Status: Recruiting Contact: Contact
Site 0152

Facility: Local Institution
Kyoto, 10408
Japan
Status: Recruiting Contact: Contact
Site 0219

Facility: Local Institution
Goyang-si, 13620
Korea, Republic of
Status: Recruiting Contact: Contact
Site 0076

Facility: Local Institution - 0203
Seongnam-si, 48108
Korea, Republic of
Status: Recruiting Contact: Contact
Site 0058

Facility: Local Institution
Busan, 41404
Korea, Republic of
Status: Recruiting Contact: Contact
Site 0154

Facility: Local Institution - 0218
Daegu, 50612
Korea, Republic of
Status: Recruiting Contact: Contact
Site 0113

Facility: Local Institution
Gyeongsangnam-do, 13496
Korea, Republic of
Status: Recruiting Contact: Contact
Site 0111

Facility: Local Institution - 0215
Seongnam-si,, 02841
Korea, Republic of
Status: Recruiting Contact: Contact
Site 0112

Facility: Local Institution
Seoul, 03080
Korea, Republic of
Status: Recruiting Contact: Contact
Site 0114

Facility: Local Institution - 0136
Seoul, 05505
Korea, Republic of
Status: Recruiting Contact: Contact
Site 0156

Facility: Local Institution
Seoul, 06351
Korea, Republic of
Status: Recruiting Contact: Contact
Site 0109

Facility: Local Institution
Seoul, 23040
Korea, Republic of
Status: Recruiting Contact: Contact
Site 0135

Facility: Local Institution - 0160
La Paz, 06720
Mexico
Status: Recruiting Contact: Contact
Site 0165

Facility: Local Institution - 0056
Monterrey, 28017
Mexico
Status: Recruiting Contact: Contact
Site 0128

Facility: Local Institution - 0105
Colima, 1066 CX
Mexico
Status: Recruiting Contact: Contact
Site 0127

Facility: Local Institution
Amsterdam, 9713 GZ
Netherlands
Status: Recruiting Contact: Contact
Site 0122

Facility: Local Institution - 0072
Groningen, 6162 BG
Netherlands
Status: Recruiting Contact: Contact
Site 0117

Facility: Local Institution
Sittard-Geleen, 1023
Netherlands
Status: Recruiting Contact: Contact
Site 0121

Facility: Local Institution
Auckland, 8011
New Zealand
Status: Recruiting Contact: Contact
Site 0124

Facility: Local Institution
Christchurch, 1714
New Zealand
Status: Recruiting Contact: N/A
Facility: Local Institution
Gralum, 1478
Norway
Status: Recruiting Contact: N/A
Facility: Local Institution - 0132
Lorenskog, 0379
Norway
Status: Recruiting Contact: N/A
Facility: Local Institution
Oslo, 1649-035
Norway
Status: Recruiting Contact: N/A
Facility: Local Institution
Lisboa, 4200-072
Portugal
Status: Recruiting Contact: N/A
Facility: Local Institution
Porto, 400015
Portugal
Status: Recruiting Contact: N/A
Facility: Local Institution - 0219
Cluj-Napoca, 200347
Romania
Status: Recruiting Contact: N/A
Facility: Local Institution - 0076
Craiova, 022328
Romania
Status: Recruiting Contact: N/A
Facility: Local Institution - 0058
Sector 2, 194044
Romania
Status: Recruiting Contact: N/A
Facility: Local Institution
Singapore, 27003
Singapore
Status: Recruiting Contact: N/A
Facility: Local Institution - 0113
Lugo, 28007
Spain
Status: Recruiting Contact: N/A
Facility: Local Institution - 0111
Madrid, 28033
Spain
Status: Recruiting Contact: N/A
Facility: Local Institution
Madrid, 28041
Spain
Status: Recruiting Contact: N/A
Facility: Local Institution
Madrid, 29010
Spain
Status: Recruiting Contact: N/A
Facility: Local Institution - 0156
Malaga, 41013
Spain
Status: Recruiting Contact: N/A
Facility: Local Institution - 0109
Sevilla, 833401
Spain
Status: Recruiting Contact: N/A
Facility: Local Institution - 0135
Kaohsiung, 407219
Taiwan
Status: Recruiting Contact: N/A
Facility: Local Institution
Taichung, 100229
Taiwan
Status: Recruiting Contact: N/A
Facility: Local Institution
Taipei City, 11217
Taiwan
Status: Recruiting Contact: N/A
Facility: Local Institution - 0139
Taipei, CM1 7ET
Taiwan
Status: Recruiting Contact: N/A
Facility: Local Institution
Chelmsford, YO31 8HE
United Kingdom
Status: Recruiting Contact: N/A
Facility: Local Institution
York, G12 0YN
United Kingdom
Status: Recruiting Contact: N/A
Facility: Local Institution - 0122
Glasgow, LA1 4RP
United Kingdom
Status: Recruiting Contact: N/A
Facility: Local Institution
Lancaster, SE1 9RT
United Kingdom
Status: Recruiting Contact: N/A
Facility: Local Institution
London, OX3 7LE
United Kingdom
Status: Recruiting Contact: N/A
Facility: Local Institution
Oxford,
United Kingdom
Status: Recruiting Contact: N/A