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Brief Title: Neoadjuvant Chemotherapy Alone Versus Neoadjuvant Chemotherapy Plus Nivolumab or Nivolumab and BMS-986205, Followed by Continued Post- Surgery Therapy With Nivolumab or Nivolumab and BMS-986205 in Participants With Muscle- Invasive Bladder Cancer

A Phase 3, Randomized, Study of Neoadjuvant Chemotherapy Alone Versus Neoadjuvant Chemotherapy Plus Nivolumab or Nivolumab and BMS-986205, Followed by Continued Post- Surgery Therapy With Nivolumab or Nivolumab and BMS-986205 in Participants With Muscle- Invasive Bladder Cancer

INTRODUCTION

  • Org Study ID: CA017-078
  • Secondary ID: 2017-004692-31
  • NTC ID: NCT03661320
  • Sponsor: Bristol-Myers Squibb
BMS Clinical Trial Information, BMS Clinical Trial Patient Recruiting, FDA Safety Alerts and Recalls

DESCRIPTION

Who is this trial for?

Patients with muscle-invasive bladder cancer who are eligible for radical cystectomy

What is the goal of this study?

To study the effects of the combination of drugs over time in patients who remain free of disease complications (EFS) and overall survival.

Summary

A phase 3, research study to evaluate nivolumab + chemotherapy or nivolumab/ BMS-986205 + chemotherapy followed by continued Immuno-Oncology therapy after radical cystectomy (RC) compared with neoadjuvant standard of care (SOC) chemotherapy alone in patients with muscle-invasive bladder cancer.

Background

MIBC patients have a 50% 5 year survival rate after radical cystectomy surgery (surgery to remove bladder and nearby tissue) and a return of cancer rate, 30-54%. 1.  Therefore, additional treatment before and/or after surgery is often considered to lower the chance that the cancer returns.  Clinical studies are research tests of an investigational drug or drugs in people.  A drug must be tested in clinical studies before it may be used for patients in the general public.

You may be eligible for this clinical study if you:

Have muscle -invasive bladder cancer, cancer that has spread to the muscle wall of the bladder

Plan to have a radical cystectomy surgery, surgery to remove bladder and nearby tissue

Do not have an autoimmune disease

Are eligible for cisplatin treatment

Participation in this clinical trial is determined using the full eligibility criteria. Some key eligibility criteria are above. To prescreen for this study or other bladder cancer studies, please take the Bladder Cancer Screener on BMS Study Connect.

Gender: All          Minimum Age: 18 Years          Maximum Age: N/A

Study Design

Patients enrolled in the trial will be randomly assigned to one of the following study treatment arms

  1. pre-surgery chemotherapy followed by surgery then standard of care observation
  2. pre-surgery chemotherapy plus Nivolumab followed by surgery then chemotherapy and Nivolumab
  3. pre-surgery chemotherapy plus Nivolumab and investigational drug followed by surgery then chemotherapy and Nivolumab and investigational drug

Considering a clinical trial?

There is a lot to think about when considering a clinical trial.

Download this pdf to discuss 2 clinical trial options with your doctor.

Visit BMSSTUDYCONNECT.com/ to learn move and to take a screener to see if you qualify for this or other trials.

BRIEF SUMMARY

A study to evaluate nivolumab + chemotherapy or nivolumab/ BMS-986205 + chemotherapy followed by continued Immuno-Oncology therapy after radical cystectomy (RC) compared with neoadjuvant standard of care (SOC) chemotherapy alone in patients with muscle-invasive bladder cancer (MIBC)

  • Overall Status
    Recruiting
  • Start Date
    October 12, 2018
  • Phase
    Phase 3
  • Study Type
    Interventional

PRIMARY OUTCOMES

Primary Outcome 1 - Measure: Pathological Complete Response (pCR) rate, in all randomized participants

Primary Outcome 1 - Timeframe: Approx. 39 months

Primary Outcome 2 - Measure: Event-Free Survival (EFS), in all randomized participants

Primary Outcome 2 - Timeframe: Approx. 57 months

CONDITION

  • Bladder Cancer
  • Muscle-Invasive Bladder Cancer
  • BMS-986205

ELIGIBILITY

Inclusion Criteria:
Participants with MIBC, clinical stage T2-T4a, N0 (<10 mm on CT or MRI), M0, diagnosed at TURBT and confirmed by radiographic imaging. Variant histology is acceptable if there is a predominant urothelial component. - Participant must be deemed eligible for Radial Cystectomy (RC) by his/her oncologist and/or urologist, and must agree to undergo Radial Cystectomy (RC) after completion of neoadjuvant therapy. - Eastern Cooperative Oncology Group (ECOG) Performance Status 0 or 1
Exclusion Criteria:
Clinical evidence of positive LN (≥ 10 mm in short axis) or metastatic bladder cancer

- Prior systemic therapy, radiation therapy, or surgery for bladder cancer other than TURBT or biopsies is also not permitted

- Ineligible to receive cisplatin due to Grade 2 or higher peripheral neuropathy or audiometric hearing loss, or calculated (Cockcroft-Gault formula) GFR or measured (24-hour urine) creatinine clearance (CrCl) < 50 mL/min

Gender: All

Minimum Age: 18 Years

Maximum Age: N/A

Healthy Volunteers: No

OFFICIAL INFORMATION

Name: Bristol-Myers Squibb

Role: Study Director

Affiliation: Bristol-Myers Squibb

Overall Contact

Name: Bristol-Myers Squibb

Phone: please email:

Email: Clinical.Trials@bms.com

LOCATION

Facility Status Contact
Facility: Arizona Oncology Associates
Tucson, Arizona 85711
United States
Status: Recruiting Contact: Contact
Site 0055
850-696-4423
Facility: Rocky Mountain Cancer Centers Llp
Littleton, Colorado 80120-4413
United States
Status: Recruiting Contact: Contact
Madhuri Bajaj, Site 0006
617975742857428
Facility: Woodlands Medical Specialists, Pa
Pensacola, Florida 32503
United States
Status: Recruiting Contact: Contact
Guru Sonpavde, Site 0209
763-712-2100
Facility: Northside Hospital
Atlanta, Georgia 30342
United States
Status: Recruiting Contact: Contact
Samith Kochuparambil, Site 0025
402-559-8649
Facility: The University Of Chicago
Chicago, Illinois 60637
United States
Status: Recruiting Contact: Contact
Ralph Hauke, Site 0183
757-262-4633
Facility: Illinois Cancer Care
Peoria, Illinois 61615
United States
Status: Recruiting Contact: Contact
Benjamin Teply, Site 0001
518-489-3612
Facility: Maryland Oncology Hematology, P.A.
Columbia, Maryland 21044
United States
Status: Recruiting Contact: Contact
David Shaffer, Site 0029
216-445-1690
Facility: Beth Israel Deaconess Medical Center
Boston, Massachusetts 02215
United States
Status: Recruiting Contact: Contact
Emerson Lim, Site 0047
971-708-7600
Facility: Cancer Center At Milford Regional Medical Center
Boston, Massachusetts 02215
United States
Status: Recruiting Contact: Contact
Shilpa Gupta, Site 0191
843-792-9007
Facility: Dana Farber Cancer Institute
Boston, Massachusetts 02215
United States
Status: Recruiting Contact: Contact
Ian Schnadig, Site 0028
414-805-4603
Facility: Minnesota Oncology Hematology
Minneapolis, Minnesota 55404
United States
Status: Recruiting Contact: Contact
Theodore Gourdin, Site 0189
512-427-9468
Facility: Oncology Hematology West P.C. dba Nebraska Cancer Specialists
Omaha, Nebraska 68130
United States
Status: Recruiting Contact: Contact
Jeffrey Yorio, Site 0030
+549113149395
Facility: University Of Nebraska Medical Center
Omaha, Nebraska 68198-6840
United States
Status: Recruiting Contact: Contact
Mark Fleming, Site 0023
+5443041081
Facility: Comprehensive Cancer Centers Of Nevada
Las Vegas, Nevada 89169
United States
Status: Recruiting Contact: Contact
Juan Pablo Sade, Site 0051
+5411482770003228
Facility: New York Oncology Hematology, Pc
Albany, New York 12208
United States
Status: Recruiting Contact: Contact
Gabriela Gatica, Site 0151
+61280374133
Facility: Columbia University Medical Center (Cumc)
New York, New York 10032
United States
Status: Recruiting Contact: Contact
Site 0130
+61394969861
Facility: Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio 44195
United States
Status: Recruiting Contact: Contact
Alison Zhang, Site 0157
+61894389023
Facility: Northwest Cancer Specialists, Pc
Tigard, Oregon 97223
United States
Status: Recruiting Contact: Contact
Laurence Krieger, Site 0043
+435125042333
Facility: Medical University Of South Carolina
Charleston, South Carolina 29425
United States
Status: Recruiting Contact: Contact
Rohit Joshi, Site 0143
+43273290044161
Facility: Vanderbilt University Medical Center
Nashville, Tennessee 37232
United States
Status: Recruiting Contact: Contact
Andrew Weickhardt, Site 0037
+43732076774445
Facility: Texas Oncology-Central Austin Cancer Center
Austin, Texas 78731
United States
Status: Recruiting Contact: Contact
Sanjay Mukhedkar, Site 0038
+4314040054780
Facility: Virginia Oncology Associates
Norfolk, Virginia 23502
United States
Status: Recruiting Contact: Contact
Wolfgang Loidl, Site 0011
+555533319393
Facility: Instituto Medico Especializado Alexander Fleming
Capital Federal, Buenos Aires 1426
Argentina
Status: Recruiting Contact: Contact
Shahrokh Shariat, Site 0012
+555133142965
Facility: Hospital Britanico De Buenos Aires
Ciudad Autónoma de Buenos Aires, Buenos Aires 1280
Argentina
Status: Recruiting Contact: Contact
Site 0060
+555133203039
Facility: Hospital Aleman
Ciudad Autonoma Buenos Aires, Distrito Federal 1118
Argentina
Status: Recruiting Contact: Contact
Site 0063
+551733216637
Facility: Local Institution
Garran, Australian Capital Territory 2605
Australia
Status: Recruiting Contact: Contact
Site 0062
+551436021397
Facility: Local Institution
Kingswood, New South Wales 2747
Australia
Status: Recruiting Contact: Contact
Karine da Trindade, Site 0094
+551732015054
Facility: Macquarie University
Macquarie University, New South Wales 2109
Australia
Status: Recruiting Contact: Contact
Luciano Viana, Site 0099
552132076564
Facility: Northern Cancer institute
St Leonards, New South Wales 2065
Australia
Status: Recruiting Contact: Contact
Fábio Franke, Site 0092
+56988039180
Facility: Calvary Hospital
North Adelaide, South Australia 5006
Australia
Status: Recruiting Contact: Contact
Pedro Isaacsson Velho, Site 0212
+56229788973
Facility: Austin Hospital
Heidelberg, Victoria 3084
Australia
Status: Recruiting Contact: Contact
Andre Fay, Site 0097
56954240753
Facility: St John of God Murdoch Hospital
Murdoch, Western Australia 6150
Australia
Status: Recruiting Contact: Contact
Joao Antonio Junior, Site 0098
+5624457254
Facility: Klinikum Klagenfurt Am Woerthersee
Klagenfurt Am Woerthersee, Ceara 9020
Austria
Status: Recruiting Contact: Contact
Patricia Beato, Site 0095
33298223333
Facility: Universitaetsklinikum Krems
Krems, Minas Gerais 3500
Austria
Status: Recruiting Contact: Contact
Gustavo Girotto, Site 0093
33322455499
Facility: Krankenhaus der Elisabethinen Linz GmbH
Linz, RIO Grande DO SUL 4010
Austria
Status: Recruiting Contact: Contact
Victor Marcondes Lopes dos Santos, Site 0164
33241356494
Facility: AKH Allgemeines Krankenhaus Wien
Wien, RIO Grande DO SUL 1090
Austria
Status: Recruiting Contact: Contact
Site 0214
33370632403
Facility: Local Institution
Bruxelles, Rio Grande Do Sul 1200
Belgium
Status: Recruiting Contact: Contact
Site 0159
33556333333
Facility: Local Institution
Gent, Sao Paulo 9000
Belgium
Status: Recruiting Contact: Contact
Site 0182
33473278186
Facility: Local Institution
Wilrijk, Sao Paulo 2610
Belgium
Status: Recruiting Contact: Contact
Site 0190
33476765451
Facility: Oncocentro Servico Medicos e Hospitalares Ltda
Fortaleza, British Columbia 60130-241
Brazil
Status: Recruiting Contact: Contact
Carolina Ibanez, Site 0053
33496196234
Facility: Hospital Marcio Cunha
Ipatinga, British Columbia 35160-158
Brazil
Status: Recruiting Contact: Contact
Olga Barajas, Site 0052
33467612304
Facility: Associacao Hospital de Caridade Ijui
Ijui, Ontario 98700-000
Brazil
Status: Recruiting Contact: Contact
Carlos Rojas, Site 0210
33492031514
Facility: Hospital Moinhos de Vento
Porto Alegre, Quebec 90035-001
Brazil
Status: Recruiting Contact: Contact
Sergio Panay, Site 0054
33156616166
Facility: Hospital Sao Lucas Da Pucrs
Porto Alegre, Quebec 90610-000
Brazil
Status: Recruiting Contact: Contact
Site 0201
33478864324
Facility: Fundacao Pio Xii Hosp Cancer De Barretos
Barretos, Metropolitana 14780-070
Brazil
Status: Recruiting Contact: Contact
Nicolas Villarreal, Site 0104
33240679900
Facility: Fundacao Doutor Amaral Carvalho
Jau, Metropolitana 17210-080
Brazil
Status: Recruiting Contact: Contact
Fernando Oviedo Martinez, Site 0103
3388115141
Facility: Hospital De Base Da Faculdade De Medicina De Rio Preto
Sao Jose Do Rio Preto, Metropolitana 15090-000
Brazil
Status: Recruiting Contact: Contact
Site 0148
33531155180
Facility: Inca - Instituto Nacional Do Cancer
Rio De Janeiro, Metropolitana 20231-050
Brazil
Status: Recruiting Contact: Contact
Site 0145
+492418088017
Facility: Local Institution
Kelowna, Hokkaido V1Y 5L3
Canada
Status: Recruiting Contact: Contact
Pierre Bigot, Site 0198
+49551398656
Facility: Local Institution
North York, Hokkaido M2K 1E1
Canada
Status: Recruiting Contact: Contact
Antoine Thiery-Vuillemin, Site 0101
+4923234995252
Facility: Local Institution
Chicoutimi, Hokkaido G7H 5H6
Canada
Status: Recruiting Contact: Contact
Guilhem Roubaud, Site 0217
+4936419329901
Facility: Local Institution
Montreal, Ibaraki H3T 1M5
Canada
Status: Recruiting Contact: Contact
Hakim Mahammedi, Site 0199
+4945150043699
Facility: Pontificia Universidad Catolica de Chile
Santiago, Kagawa 8330024
Chile
Status: Recruiting Contact: Contact
Christophe Tournigand, Site 0204
+493916715036
Facility: Hospital Clinico de la Universidad De Chile
Santiago, Kanagawa 8380456
Chile
Status: Recruiting Contact: Contact
Mathieu LARAMAS, Site 0206
+496131172301
Facility: Centro de Investigacion Clinica Bradford Hill
Santiago, Niigata 8420383
Chile
Status: Recruiting Contact: Contact
Jean-Baptiste Paoli, Site 0075
+498941402552
Facility: Fundacion Arturo Lopez Perez
Santiago, Osaka 681004
Chile
Status: Recruiting Contact: Contact
Diego Tosi, Site 0200
+499113983085
Facility: Local Institution
Colombia, Osaka 230003
Colombia
Status: Recruiting Contact: Contact
Delphine Borchiellini, Site 0074
+496512081921
Facility: Foscal Internacional
Bucaramanga, Saitama 9000
Colombia
Status: Recruiting Contact: Contact
Mostefa Bennamoun, Site 0163
+302413502124
Facility: Oncomedica S.A.
Monteria, Shizuoka 8000
Colombia
Status: Recruiting Contact: Contact
Denis Maillet, Site 0020
+390805555355
Facility: Local Institution
Helsinki, Gyeonggi-do 20251
Finland
Status: Recruiting Contact: Contact
Julius van Essen, Site 0078
+39050992070
Facility: Local Institution
Tampere, BAJA Californa SUR 29609
Finland
Status: Recruiting Contact: Contact
Thomas Steiner, Site 0015
+390630155202
Facility: Local Institution
Turku, Distrito Federal 80054
Finland
Status: Recruiting Contact: Contact
Susanne Krege, Site 0081
+40742206212
Facility: Hopital Morvan
Brest, Jalisco 49100
France
Status: Recruiting Contact: Contact
Severine Banek, Site 0086
+40727774974
Facility: CHU Amiens - Picardie
Amiens, Nuevo LEON 25030
France
Status: Recruiting Contact: Contact
Arne Strauss, Site 0080

Facility: Chu Angers
Angers, Essex 33075
France
Status: Recruiting Contact: Contact
Florian Roghmann, Site 0013

Facility: Chu Jean Minjoz
Besancon Cedex, Yorkshire 33076
France
Status: Recruiting Contact: Contact
Marc-Oliver Grimm, Site 0010

Facility: Institut Bergonie
Bordeaux, 94010
France
Status: Recruiting Contact: Contact
Martin Schostak, Site 0079

Facility: Centre Jean Perrin
Clermont-ferrand, 38043
France
Status: Recruiting Contact: Contact
Igor Tsaur, Site 0100

Facility: Chu Henri Mondor
Creteil Cedex, 13273
France
Status: Recruiting Contact: Contact
Margitta Retz, Site 0082

Facility: CHU Michallon
La Tronche, 34298
France
Status: Recruiting Contact: Contact
Clemens Huettenbrink, Site 0016

Facility: Hopital Prive CLAIRVAL
Marseille, 06189
France
Status: Recruiting Contact: Contact
Andreas Neisius, Site 0085

Facility: Institut du Cancer de Montpellier
Montpellier Cedex 5, 75014
France
Status: Recruiting Contact: Contact
Aristotelis Bamias, Site 0194

Facility: Centre Antoine Lacassagne
Nice, 69310
France
Status: Recruiting Contact: Contact
Evangelos Bournakis, Site 0195

Facility: Institut Mutualiste Montsouris
Paris, 35042
France
Status: Recruiting Contact: Contact
Athanasios Kotsakis, Site 0031

Facility: Centre Hospitalier Lyon Sud
Pierre Benite, 44805
France
Status: Recruiting Contact: Contact
Site 0068

Facility: Centre Rene Gauducheau
Saint Herblain Cedex, 31059
France
Status: Recruiting Contact: Contact
Site 0067

Facility: ICANS-Institut de cancerologie Strasbourg Europe
Strasbourg Cedex, 52074
France
Status: Recruiting Contact: Contact
Site 0196

Facility: Institut Claudius Regaud
TOULOUSE Cedex 9, 99028
France
Status: Recruiting Contact: Contact
Emanuele Naglieri, Site 0064

Facility: Universitaetsklinikum Aachen
Aachen, 45136
Germany
Status: Recruiting Contact: Contact
Site 0193

Facility: Helios Klinikum Erfurt
Erfurt, 60590
Germany
Status: Recruiting Contact: Contact
Giuseppe Procopio, Site 0032

Facility: Klinik Essen-Mitte
Essen, 37075
Germany
Status: Recruiting Contact: Contact
Claudia Mucciarini, Site 0065

Facility: Johann Wolfgang Goethe Universitaet
Frankfurt Main, 69120
Germany
Status: Recruiting Contact: Contact
Umberto Basso, Site 0033

Facility: Universitaetsmedizin Goettingen
Goettingen, 44625
Germany
Status: Recruiting Contact: Contact
Luca Galli, Site 0034

Facility: Marien Hospital Herne
Herne, 23538
Germany
Status: Recruiting Contact: Contact
Site 0186

Facility: Universitaetsklinikum Jena
Jena, 39120
Germany
Status: Recruiting Contact: Contact
Site 0184

Facility: University Hospital Schleswig-Holstein
Luebeck, 55101
Germany
Status: Recruiting Contact: Contact
Site 0177

Facility: Universitaetsklinikum Magdeburg
Magdeburg, 81675
Germany
Status: Recruiting Contact: Contact
Site 0185

Facility: Universitaetsmedizin Der Johannes Gutenberg-Universitaet
Mainz, 90419
Germany
Status: Recruiting Contact: Contact
Site 0179

Facility: Klinikum rechts der Isar der TU
Muenchen, 54292
Germany
Status: Recruiting Contact: Contact
Site 0171

Facility: Klinikum Nuernberg Nord, Urologische Klinik
Nuernberg, 11528
Germany
Status: Recruiting Contact: Contact
Site 0169

Facility: Krankenhaus der Barmherzigen Brueder
Trier, 12462
Germany
Status: Recruiting Contact: Contact
Site 0168

Facility: University General Hospital of Athens Attikon
Chaidari, 41110
Greece
Status: Recruiting Contact: Contact
Site 0175

Facility: Metropolitan General Hospital
Holargos, 84101
Greece
Status: Recruiting Contact: Contact
Site 0176

Facility: University General Hospital of Larissa
Larissa, 3109601
Greece
Status: Recruiting Contact: Contact
Site 0170

Facility: Local Institution
Beer Sheva, 52621
Israel
Status: Recruiting Contact: Contact
Site 0178

Facility: Local Institution
Haifa, 6423906
Israel
Status: Recruiting Contact: Contact
Site 0172

Facility: Local Institution
Ramat Gan, 70124
Israel
Status: Recruiting Contact: Contact
Site 0174

Facility: Local Institution
Tel Aviv, 47014
Israel
Status: Recruiting Contact: Contact
Site 0180

Facility: IRCCS Giovanni Paolo II Istituto Oncologico
Bari, 20133
Italy
Status: Recruiting Contact: Contact
Site 0137

Facility: Local Institution
Forlì, 41012
Italy
Status: Recruiting Contact: Contact
Site 0203

Facility: IRCCS Istituto Nazionale Tumori Milano
Milano, 35128
Italy
Status: Recruiting Contact: Contact
Site 0220

Facility: Ospedale Di Carpi
Modena, 56126
Italy
Status: Recruiting Contact: Contact
Site 0218

Facility: Istituto Oncologico Veneto IOV
Padova, 00168
Italy
Status: Recruiting Contact: Contact
Site 0208

Facility: Azienda Ospedaliera Universitaria Pisana
Pisa, 485-8520
Italy
Status: Recruiting Contact: Contact
Site 0215

Facility: Fondazione Policlinico Universitario A. Gemelli
Roma, 0030804
Italy
Status: Recruiting Contact: Contact
Site 0140

Facility: Local Institution
Komaki, 060-8543
Japan
Status: Recruiting Contact: Contact
Site 0136

Facility: Local Institution
Sapporo, 0608604
Japan
Status: Recruiting Contact: Contact
Site 0211

Facility: Local Institution
Sapporo, 3058576
Japan
Status: Recruiting Contact: Contact
Site 0138

Facility: Local Institution
Sapporo, 761-0793
Japan
Status: Recruiting Contact: Contact
Site 0160

Facility: Local Institution
Tsukuba-shi, 222-0036
Japan
Status: Recruiting Contact: Contact
Site 0161

Facility: Local Institution
Kita-gun, 9518520
Japan
Status: Recruiting Contact: Contact
Site 0056

Facility: Local Institution
Yokohama, 589-8511
Japan
Status: Recruiting Contact: Contact
Site 0105

Facility: Local Institution
Niigata-shi, 5698686
Japan
Status: Recruiting Contact: Contact
Site 0070

Facility: Local Institution
Osakasayama, 3501298
Japan
Status: Recruiting Contact: Contact
Site 0072

Facility: Local Institution
Takatsuki City, 4313192
Japan
Status: Recruiting Contact: Contact
Site 0073

Facility: Local Institution
Hidaka-shi, 1058470
Japan
Status: Recruiting Contact: Contact
Site 0087

Facility: Local Institution
Hamamatsu-shi, 160-8582
Japan
Status: Recruiting Contact: Contact
Site 0089

Facility: Local Institution
Minato-ku, 812-8582
Japan
Status: Recruiting Contact: Contact
Site 0158

Facility: Local Institution
Shinjuku-ku, 606-8507
Japan
Status: Recruiting Contact: Contact
Site 0132

Facility: Local Institution
Fukuoka, 10408
Japan
Status: Recruiting Contact: Contact
Site 0133

Facility: Local Institution
Kyoto, 13620
Japan
Status: Recruiting Contact: Contact
Site 0153

Facility: Local Institution
Goyang-si, 48108
Korea, Republic of
Status: Recruiting Contact: Contact
Site 0152

Facility: Local Institution
Seongnam-si, 41404
Korea, Republic of
Status: Recruiting Contact: Contact
Aurelia Alexandru, Site 0058

Facility: Local Institution
Busan, 50612
Korea, Republic of
Status: Recruiting Contact: Contact
Site 0219

Facility: Local Institution
Daegu, 13496
Korea, Republic of
Status: Recruiting Contact: Contact
Michael Schenker, Site 0076

Facility: Local Institution
Gyeongsangnam-do, 02841
Korea, Republic of
Status: Recruiting Contact: Contact
Site 0044

Facility: Local Institution
Seongnam-si,, 03080
Korea, Republic of
Status: Recruiting Contact: Contact
Site 0057

Facility: Local Institution
Seoul, 05505
Korea, Republic of
Status: Recruiting Contact: Contact
Site 0154

Facility: Local Institution
Seoul, 06351
Korea, Republic of
Status: Recruiting Contact: Contact
Site 0113

Facility: Local Institution
Seoul, 23040
Korea, Republic of
Status: Recruiting Contact: Contact
Site 0111

Facility: Local Institution
Seoul, 06720
Korea, Republic of
Status: Recruiting Contact: Contact
Site 0112

Facility: Local Institution
La Paz, 45050
Mexico
Status: Recruiting Contact: Contact
Site 0114

Facility: Local Institution
Monterrey, 1066 CX
Mexico
Status: Recruiting Contact: Contact
Site 0135

Facility: Local Institution
Colima, 9713 GZ
Mexico
Status: Recruiting Contact: Contact
Site 0165

Facility: Local Institution
Amsterdam, 6162 BG
Netherlands
Status: Recruiting Contact: Contact
Site 0141

Facility: Local Institution
Groningen, 1023
Netherlands
Status: Recruiting Contact: Contact
Site 0139

Facility: Local Institution
Sittard-Geleen, 8011
Netherlands
Status: Recruiting Contact: Contact
Site 0128

Facility: Local Institution
Auckland, 1714
New Zealand
Status: Recruiting Contact: Contact
Site 0127

Facility: Local Institution
Christchurch, 1478
New Zealand
Status: Recruiting Contact: Contact
Site 0122

Facility: Local Institution
Gralum, 0379
Norway
Status: Recruiting Contact: Contact
Site 0117

Facility: Local Institution
Lorenskog, 1649-035
Norway
Status: Recruiting Contact: Contact
Site 0121

Facility: Local Institution
Oslo, 4200-072
Norway
Status: Recruiting Contact: Contact
Site 0124

Facility: Local Institution
Lisboa, 020122
Portugal
Status: Recruiting Contact: N/A
Facility: Institute Of Oncology "Prof.Dr.Alexandru Trestioreanu" Bucha
Bucharest, 200347
Romania
Status: Recruiting Contact: N/A
Facility: Local Institution
Cluj-Napoca, 194044
Romania
Status: Recruiting Contact: N/A
Facility: Sf. Nectarie Oncology Center
Craiova, 197758
Romania
Status: Recruiting Contact: N/A
Facility: Local Institution
Saint-Petersburg, 169610
Russian Federation
Status: Recruiting Contact: N/A
Facility: Local Institution
St Petersburg, 27003
Russian Federation
Status: Recruiting Contact: N/A
Facility: Local Institution
Singapore, 28007
Singapore
Status: Recruiting Contact: N/A
Facility: Local Institution
Lugo, 28033
Spain
Status: Recruiting Contact: N/A
Facility: Local Institution
Madrid, 28041
Spain
Status: Recruiting Contact: N/A
Facility: Local Institution
Madrid, 29010
Spain
Status: Recruiting Contact: N/A
Facility: Local Institution
Madrid, 41013
Spain
Status: Recruiting Contact: N/A
Facility: Local Institution
Malaga, 833401
Spain
Status: Recruiting Contact: N/A
Facility: Local Institution
Sevilla, 407219
Spain
Status: Recruiting Contact: N/A
Facility: Local Institution
Kaohsiung, 100229
Taiwan
Status: Recruiting Contact: N/A
Facility: Local Institution
Taichung, 11217
Taiwan
Status: Recruiting Contact: N/A
Facility: Local Institution
Taipei City, CM1 7ET
Taiwan
Status: Recruiting Contact: N/A
Facility: Local Institution
Taipei, YO31 8HE
Taiwan
Status: Recruiting Contact: N/A
Facility: Local Institution
Chelmsford, G12 0YN
United Kingdom
Status: Recruiting Contact: N/A
Facility: Local Institution
York, LA1 4RP
United Kingdom
Status: Recruiting Contact: N/A
Facility: Local Institution
Glasgow, SE1 9RT
United Kingdom
Status: Recruiting Contact: N/A
Facility: Local Institution
Lancaster, OX3 7LE
United Kingdom
Status: Recruiting Contact: N/A
Facility: Local Institution
London,
United Kingdom
Status: Recruiting Contact: N/A
Facility: Local Institution
Oxford,
United Kingdom
Status: Recruiting Contact: N/A