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Brief Title: Study of Dose-Dense Gemcitabine Plus Cisplatin (ddGC) in Patients With Muscle-Invasive Bladder Cancer With Bladder Preservation for Those Patients Whose Tumors Harbor Deleterious DNA Damage Response (DDR) Gene Alterations

A Phase II Study of Gemcitabine Plus Cisplatin Chemotherapy in Patients With Muscle-invasive Bladder Cancer With Bladder Preservation for Those Patients Whose Tumors Harbor Deleterious DNA Damage Response (DDR) Gene Alterations

INTRODUCTION

  • Org Study ID: A031701
  • Secondary ID: N/A
  • NCT ID: NCT03609216
  • Sponsor: Alliance for Clinical Trials in Oncology

BRIEF SUMMARY

This phase II trial studies how well gemcitabine hydrochloride and cisplatin work in treating participants with invasive bladder urothelial cancer. Drugs used in chemotherapy, such as gemcitabine hydrochloride and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

DETAILED DESCRIPTION

PRIMARY OBJECTIVES:

I. To determine the 3-year event free survival, defined as the proportion of patients without invasive or metastatic recurrence following definitive gemcitabine hydrochloride (gemcitabine) and cisplatin (standard or dose-dense) chemotherapy in those patients whose pre-treatment transurethral resection of bladder tumor (TURBT) tumors harbor deleterious DDR gene alterations and who achieve < cT1 response to chemotherapy.

SECONDARY OBJECTIVES:

I. To determine the clinical response rate (< cT1) for patients harboring deleterious DDR gene alterations following dose dense gemcitabine and cisplatin.

II. To determine the bladder-intact and overall survival for DDR-altered patients with < cT1.

III. For DDR gene altered patients who elect radical cystectomy despite < cT1, to determine the pT0 rate in this patient population.

IV. To determine the pathologic response rate at cystectomy and 3-year recurrence-free and overall survival for patients without DDR mutations who are registered onto this trial.

V. To assess the local treatment burden (Bacillus Calmette-Guerin [BCG] therapy, resection of non-invasive disease, checkpoint blockade) over time in the bladder-sparing group.

VI. To determine the bladder-intact disease-free survival in patients who elect to undergo chemoradiation therapy in the DDR mutant group and the DDR wild-type group.

OUTLINE:

Participants receive gemcitabine hydrochloride intravenously (IV) over 30 minutes on day 1, cisplatin IV on days 1 and 2, and pegfilgrastim subcutaneously (SC) on day 3. Treatment repeats every 14 days for up to 6 courses in the absence of disease progression or unaccepted toxicity. Participants are then assigned to 1 of 2 arms.

ARM I: Participants with DDR gene alteration and disease stage < cT1 undergo bladder sparing.

ARM II: Participants with DDR gene alteration and disease stage >= cT1 or participants without DDR gene alteration undergo radical cystectomy or chemoradiotherapy.

After completion of study treatment, participants are followed up for 5 years.

  • Overall Status
    Recruiting
  • Start Date
    August 1, 2018
  • Phase
    Phase 2
  • Study Type
    Interventional

PRIMARY OUTCOMES

Primary Outcome 1 - Measure: Proportion of patients who are recurrence-free within the DDR mutated group who undergo the bladder sparing approach

Primary Outcome 1 - Timeframe: At 3 years

CONDITION

  • Infiltrating Bladder Urothelial Carcinoma
  • Stage II Bladder Urothelial Carcinoma
  • Stage III Bladder Urothelial Carcinoma

ELIGIBILITY

Inclusion Criteria:
* Step 1 Patient Registration Eligibility Criteria

- * Histologically confirmed muscle-invasive urothelial carcinoma of the bladder. Urothelial carcinoma invading into the prostatic stroma with no histologic muscle invasion is allowed, provided the extent of disease is confirmed via imaging and/or examination under anesthesia (EUA). The diagnostic TURBT sample must have been obtained within 60 days prior to registration

- * 20 unstained slides (10 micron thickness) of formalin-fixed paraffin-embedded (FFPE) pre-treatment diagnostic transurethral resection (TUR) specimen available (for sequencing), with 2 (5 micron) slides at the start and end of the 20 slides, for a total of 22 unstained slides. An FFPE block is also acceptable

- * Clinical stage T2-T4aN0/xM0 disease

- * Medically appropriate candidate for radical cystectomy as assessed by surgeon

- * No concomitant multifocal carcinoma in situ; a single focus is allowed

- * A single muscle-invasive bladder tumor measuring ≤5 cm in size as defined by the surgeons at cystoscopic evaluation. When documented, pathologic size at cystoscopy and TURBT will take precedence over radiographic measurements of tumor size.

- * No clinical or radiographic evidence for locally advanced or metastatic disease

- * No prior anti-PD-1 or anti PD-L1 therapies, or systemic chemotherapy within the past 5 years (prior intravesical induction immunotherapy for non-muscle invasive disease is allowed, defined as BCG x6 doses and maintenance therapy); BCG refractory disease, defined as disease recurrence within 3 months of BCG therapy, is not allowed. Intravesical chemotherapy is allowed.

- * No prior radiation therapy to the bladder or prostate

- * No major surgery or radiation therapy =< 4 weeks of registration (TURBT is allowed). - * Not pregnant and not nursing. This study involves an agent that has known genotoxic, mutagenic and teratogenic effects. For women of childbearing potential only, a negative pregnancy test done =< 14 days prior to registration is required - * Eastern Cooperative Oncology Group (ECOG) performance status 0-1 - * Absolute neutrophil count (ANC) >= 1,000/mm^3

- * Platelet count >= 100,000/mm^3

- * Calculated creatinine clearance ≥ 55 mL/min using formula per institutional standard or investigator's discretion. The same formula should be used to calculate all subsequent creatinine clearances.

- * Total bilirubin =< 1.5 x upper limit of normal (ULN)
* (For patients with documented Gilbert's syndrome Total Bilirubin =< 3 x ULN) - * Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =< 2.5 x ULN - * Alkaline phosphatase =< 2.5 x ULN - * No evidence of New York Heart Association (NYHA) functional class III or IV heart disease - * No ongoing cardiac dysrhythmias of National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) version 5.0 grade >= 2

- * No pre-existing sensory grade >= 2 neuropathy

- * No pre-existing grade >= 2 hearing loss

- * No serious intercurrent medical or psychiatric illness, including serious active infection

- * None of the following within the 6 months prior to study drug administration: myocardial infarction, severe/unstable angina, coronary/peripheral artery bypass graft, symptomatic congestive heart failure, cerebrovascular accident, or transient ischemic attack

- * No known human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS)-related illness or other active infection. HIV-positive patients on combination antiretroviral therapy are ineligible because of the potential for pharmacokinetic interactions with the drugs used in this trial. In addition, these patients are at increased risk of lethal infections when treated with marrow-suppressive therapy. Appropriate studies will be undertaken in patients receiving combination antiretroviral therapy, when indicated

- * No history of allergic reaction attributed to compounds of similar chemical or biologic composition to the agents used in this study

- * No concurrent treatment on another clinical trial; supportive care trials or non-therapeutic trials (e.g., quality of life) are allowed

- * No prior malignancy except for: adequately treated basal or squamous cell skin cancer, in situ cervical cancer, adequately treated stage I or II cancer from which the patient is currently in complete remission, or any other cancer from which the patient has been disease free for five years. Patients with localized prostate cancer who are being followed by an active surveillance program are also eligible

- * Step 2 Patient Registration Eligibility Criteria

- * Patients must have completed 4 or more cycles of protocol-directed chemotherapy and DDR gene results must be available

- * Step 3 Patient Registration Eligibility Criteria (only patients with a DDR gene alteration)

- * Deleterious alteration within 1 or more of 9 pre-defined DDR genes within the pre-treatment TURBT deoxyribonucleic acid (DNA)

- * Cystoscopy and imaging performed to determine stage/treatment assignment

Gender: All

Minimum Age: 18 Years

Maximum Age: N/A

Healthy Volunteers: No

OFFICIAL INFORMATION

Name: Gopa Iyer, MD

Role: Study Chair

Affiliation: Memorial Sloan Kettering Cancer Center

Overall Contact

Name: Gopa Iyer, MD

Phone: 646-888-4737

Email: [email protected]

LOCATION

Facility Status Contact
Facility: Fairbanks Memorial Hospital
Fairbanks, Alaska 99701
United States
Status: Recruiting Contact: Contact
Site Public Contact
907-458-3043
[email protected]

Principal Investigator
Nicholas J. DiBella

Facility: Cancer Center at Saint Joseph's
Phoenix, Arizona 85004
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Mercy Hospital Fort Smith
Fort Smith, Arkansas 72903
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-378-9373

Principal Investigator
Jay W. Carlson

Facility: University of Arkansas for Medical Sciences
Little Rock, Arkansas 72205
United States
Status: Recruiting Contact: Contact
Site Public Contact
501-686-8274

Principal Investigator
Shi-Ming Tu

Facility: Mission Hope Medical Oncology - Arroyo Grande
Arroyo Grande, California 93420
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Mercy Cancer Center - Carmichael
Carmichael, California 95608
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Mercy San Juan Medical Center
Carmichael, California 95608
United States
Status: Recruiting Contact: Contact
Site Public Contact
916-556-3301
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Mercy Cancer Center - Elk Grove
Elk Grove, California 95758
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Contra Costa Regional Medical Center
Martinez, California 94553-3156
United States
Status: Recruiting Contact: Contact
Site Public Contact
925-957-5400

Principal Investigator
Nicholas J. DiBella

Facility: Fremont - Rideout Cancer Center
Marysville, California 95901
United States
Status: Recruiting Contact: Contact
Site Public Contact
530-749-4400

Principal Investigator
Mamta Parikh

Facility: Mercy Cancer Center - Rocklin
Rocklin, California 95765
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Mercy Cancer Center - Sacramento
Sacramento, California 95816
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: University of California Davis Comprehensive Cancer Center
Sacramento, California 95817
United States
Status: Recruiting Contact: Contact
Site Public Contact
916-734-3089

Principal Investigator
Mamta Parikh

Facility: Pacific Central Coast Health Center-San Luis Obispo
San Luis Obispo, California 93401
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Mission Hope Medical Oncology - Santa Maria
Santa Maria, California 93444
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Woodland Memorial Hospital
Woodland, California 95695
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Rocky Mountain Cancer Centers-Aurora
Aurora, Colorado 80012
United States
Status: Recruiting Contact: Contact
Site Public Contact
303-777-2663
[email protected]

Principal Investigator
Nicholas J. DiBella

Facility: Rocky Mountain Cancer Centers-Boulder
Boulder, Colorado 80304
United States
Status: Recruiting Contact: Contact
Site Public Contact
303-777-2663
[email protected]

Principal Investigator
Nicholas J. DiBella

Facility: Penrose-Saint Francis Healthcare
Colorado Springs, Colorado 80907
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Rocky Mountain Cancer Centers-Penrose
Colorado Springs, Colorado 80907
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Saint Francis Cancer Center
Colorado Springs, Colorado 80923
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Presbyterian - Saint Lukes Medical Center - Health One
Denver, Colorado 80218
United States
Status: Recruiting Contact: Contact
Site Public Contact
303-777-2663
[email protected]

Principal Investigator
Nicholas J. DiBella

Facility: The Melanoma and Skin Cancer Institute
Englewood, Colorado 80113
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-316-8091
[email protected]

Principal Investigator
Nicholas J. DiBella

Facility: Saint Anthony Hospital
Lakewood, Colorado 80228
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Rocky Mountain Cancer Centers-Littleton
Littleton, Colorado 80120
United States
Status: Recruiting Contact: Contact
Site Public Contact
303-777-2663
[email protected]

Principal Investigator
Nicholas J. DiBella

Facility: Longmont United Hospital
Longmont, Colorado 80501
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Saint Mary Corwin Medical Center
Pueblo, Colorado 81004
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Rocky Mountain Cancer Centers-Thornton
Thornton, Colorado 80260
United States
Status: Recruiting Contact: Contact
Site Public Contact
303-777-2663
[email protected]

Principal Investigator
Nicholas J. DiBella

Facility: Hartford Hospital
Hartford, Connecticut 06102
United States
Status: Recruiting Contact: Contact
Site Public Contact
860-545-5363

Principal Investigator
Jeffrey M. Kamradt

Facility: Midstate Medical Center
Meriden, Connecticut 06451
United States
Status: Recruiting Contact: Contact
Site Public Contact
866-662-5678

Principal Investigator
Jeffrey M. Kamradt

Facility: The Hospital of Central Connecticut
New Britain, Connecticut 06050
United States
Status: Recruiting Contact: Contact
Site Public Contact
860-224-5660

Principal Investigator
Jeffrey M. Kamradt

Facility: Holy Cross Hospital
Fort Lauderdale, Florida 33308
United States
Status: Recruiting Contact: Contact
Site Public Contact
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: University of Florida Health Science Center - Gainesville
Gainesville, Florida 32610
United States
Status: Recruiting Contact: Contact
Site Public Contact
352-273-8010
[email protected]

Principal Investigator
Paul L. Crispen

Facility: Saint Alphonsus Cancer Care Center-Boise
Boise, Idaho 83706
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
[email protected]

Principal Investigator
John M. Schallenkamp

Facility: Saint Alphonsus Cancer Care Center-Caldwell
Caldwell, Idaho 83605
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
[email protected]

Principal Investigator
John M. Schallenkamp

Facility: Kootenai Health - Coeur d'Alene
Coeur d'Alene, Idaho 83814
United States
Status: Recruiting Contact: Contact
Site Public Contact
406-969-6060
[email protected]

Principal Investigator
John M. Schallenkamp

Facility: Idaho Urologic Institute-Meridian
Meridian, Idaho 83642
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
[email protected]

Principal Investigator
John M. Schallenkamp

Facility: Saint Alphonsus Cancer Care Center-Nampa
Nampa, Idaho 83687
United States
Status: Recruiting Contact: Contact
Site Public Contact
406-969-6060
[email protected]

Principal Investigator
John M. Schallenkamp

Facility: Kootenai Clinic Cancer Services - Post Falls
Post Falls, Idaho 83854
United States
Status: Recruiting Contact: Contact
Site Public Contact
406-969-6060
[email protected]

Principal Investigator
John M. Schallenkamp

Facility: Rush - Copley Medical Center
Aurora, Illinois 60504
United States
Status: Recruiting Contact: Contact
Site Public Contact
630-978-6212
[email protected]

Principal Investigator
Priyank P. Patel

Facility: Illinois CancerCare-Bloomington
Bloomington, Illinois 61704
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Illinois CancerCare-Canton
Canton, Illinois 61520
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Memorial Hospital of Carbondale
Carbondale, Illinois 62902
United States
Status: Recruiting Contact: Contact
Site Public Contact
618-457-5200
[email protected]

Principal Investigator
Bryan A. Faller

Facility: SIH Cancer Institute
Carterville, Illinois 62918
United States
Status: Recruiting Contact: Contact
Site Public Contact
618-985-3333
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Illinois CancerCare-Carthage
Carthage, Illinois 62321
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Centralia Oncology Clinic
Centralia, Illinois 62801
United States
Status: Recruiting Contact: Contact
Site Public Contact
217-876-4762
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Saint Mary's Hospital
Centralia, Illinois 62801
United States
Status: Recruiting Contact: Contact
Site Public Contact
773-702-9171
[email protected]

Principal Investigator
Jay W. Carlson

Facility: Carle at The Riverfront
Danville, Illinois 61832
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-446-5532
[email protected]

Principal Investigator
Priyank P. Patel

Facility: Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois 62526
United States
Status: Recruiting Contact: Contact
Site Public Contact
217-876-4762
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Decatur Memorial Hospital
Decatur, Illinois 62526
United States
Status: Recruiting Contact: Contact
Site Public Contact
217-876-4762
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Illinois CancerCare-Dixon
Dixon, Illinois 61021
United States
Status: Recruiting Contact: Contact
Site Public Contact
815-285-7800

Principal Investigator
Bryan A. Faller

Facility: Carle Physician Group-Effingham
Effingham, Illinois 62401
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-446-5532
[email protected]

Principal Investigator
Priyank P. Patel

Facility: Crossroads Cancer Center
Effingham, Illinois 62401
United States
Status: Recruiting Contact: Contact
Site Public Contact
217-876-4762
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Illinois CancerCare-Eureka
Eureka, Illinois 61530
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Illinois CancerCare-Galesburg
Galesburg, Illinois 61401
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Ingalls Memorial Hospital
Harvey, Illinois 60426
United States
Status: Recruiting Contact: Contact
Site Public Contact
708-915-4673
[email protected]

Principal Investigator
James A. Wallace

Facility: Illinois CancerCare-Kewanee Clinic
Kewanee, Illinois 61443
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Illinois CancerCare-Macomb
Macomb, Illinois 61455
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois 61938
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-446-5532
[email protected]

Principal Investigator
Priyank P. Patel

Facility: Good Samaritan Regional Health Center
Mount Vernon, Illinois 62864
United States
Status: Recruiting Contact: Contact
Site Public Contact
618-242-4600

Principal Investigator
Jay W. Carlson

Facility: Cancer Care Center of O'Fallon
O'Fallon, Illinois 62269
United States
Status: Recruiting Contact: Contact
Site Public Contact
217-876-4762
[email protected]

Principal Investigator
Bryan A. Faller

Facility: HSHS Saint Elizabeth's Hospital
O'Fallon, Illinois 62269
United States
Status: Recruiting Contact: Contact
Site Public Contact
217-876-4762
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois 61350
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Illinois CancerCare-Pekin
Pekin, Illinois 61554
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
[email protected]

Principal Investigator
Bryan A. Faller

Facility: OSF Saint Francis Radiation Oncology at Pekin
Pekin, Illinois 61554
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Illinois CancerCare-Peoria
Peoria, Illinois 61615
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
[email protected]

Principal Investigator
Bryan A. Faller

Facility: OSF Saint Francis Radiation Oncology at Peoria Cancer Center
Peoria, Illinois 61615
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Methodist Medical Center of Illinois
Peoria, Illinois 61636
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
[email protected]

Principal Investigator
Bryan A. Faller

Facility: OSF Saint Francis Medical Center
Peoria, Illinois 61637
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Illinois CancerCare-Peru
Peru, Illinois 61354
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Valley Radiation Oncology
Peru, Illinois 61354
United States
Status: Recruiting Contact: Contact
Site Public Contact
815-664-4141

Principal Investigator
Bryan A. Faller

Facility: Illinois CancerCare-Princeton
Princeton, Illinois 61356
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Southern Illinois University School of Medicine
Springfield, Illinois 62702
United States
Status: Recruiting Contact: Contact
Site Public Contact
217-545-7929

Principal Investigator
Bryan A. Faller

Facility: Springfield Clinic
Springfield, Illinois 62702
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-444-7541

Principal Investigator
Bryan A. Faller

Facility: Memorial Medical Center
Springfield, Illinois 62781
United States
Status: Recruiting Contact: Contact
Site Public Contact
217-528-7541
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Carle Cancer Center
Urbana, Illinois 61801
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-446-5532
[email protected]

Principal Investigator
Priyank P. Patel

Facility: The Carle Foundation Hospital
Urbana, Illinois 61801
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-446-5532
[email protected]

Principal Investigator
Priyank P. Patel

Facility: Illinois CancerCare - Washington
Washington, Illinois 61571
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Reid Health
Richmond, Indiana 47374
United States
Status: Recruiting Contact: Contact
Site Public Contact
937-528-2900
[email protected]

Principal Investigator
Howard M. Gross

Facility: Central Care Cancer Center - Garden City
Garden City, Kansas 67846
United States
Status: Recruiting Contact: Contact
Site Public Contact
913-948-5588
[email protected]

Principal Investigator
Jay W. Carlson

Facility: Central Care Cancer Center - Great Bend
Great Bend, Kansas 67530
United States
Status: Recruiting Contact: Contact
Site Public Contact
913-948-5588
[email protected]

Principal Investigator
Jay W. Carlson

Facility: Saint Joseph Hospital
Lexington, Kentucky 40504
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Saint Joseph Radiation Oncology Resource Center
Lexington, Kentucky 40504
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Saint Joseph Hospital East
Lexington, Kentucky 40509
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: LSU Health Baton Rouge-North Clinic
Baton Rouge, Louisiana 70805
United States
Status: Recruiting Contact: Contact
Site Public Contact
225-765-7659
[email protected]

Principal Investigator
Marshall P. Stagg

Facility: Our Lady of the Lake Physician Group
Baton Rouge, Louisiana 70808
United States
Status: Recruiting Contact: Contact
Site Public Contact
225-765-7659
[email protected]

Principal Investigator
Marshall P. Stagg

Facility: Our Lady of The Lake
Baton Rouge, Louisiana 70808
United States
Status: Recruiting Contact: Contact
Site Public Contact
225-765-7659

Principal Investigator
Marshall P. Stagg

Facility: Louisiana Hematology Oncology Associates LLC
Baton Rouge, Louisiana 70809
United States
Status: Recruiting Contact: Contact
Site Public Contact
225-215-1353
[email protected]

Principal Investigator
Victor T. Lin

Facility: Mary Bird Perkins Cancer Center
Baton Rouge, Louisiana 70809
United States
Status: Recruiting Contact: Contact
Site Public Contact
225-215-1353
[email protected]

Principal Investigator
Victor T. Lin

Facility: Northshore Oncology Associates-Covington
Covington, Louisiana 70433
United States
Status: Recruiting Contact: Contact
Site Public Contact
225-215-1353
[email protected]

Principal Investigator
Victor T. Lin

Facility: Terrebonne General Medical Center
Houma, Louisiana 70360
United States
Status: Recruiting Contact: Contact
Site Public Contact
985-850-6300
[email protected]

Principal Investigator
Victor T. Lin

Facility: Mary Bird Perkins Cancer Center - Metairie
Metairie, Louisiana 70002
United States
Status: Recruiting Contact: Contact
Site Public Contact
504-584-6990

Principal Investigator
Victor T. Lin

Facility: East Jefferson General Hospital
Metairie, Louisiana 70006
United States
Status: Recruiting Contact: Contact
Site Public Contact
504-210-3539
[email protected]

Principal Investigator
Scott E. Delacroix

Facility: LSU Healthcare Network / Metairie Multi-Specialty Clinic
Metairie, Louisiana 70006
United States
Status: Recruiting Contact: Contact
Site Public Contact
504-210-3539
[email protected]

Principal Investigator
Scott E. Delacroix

Facility: Louisiana State University Health Science Center
New Orleans, Louisiana 70112
United States
Status: Recruiting Contact: Contact
Site Public Contact
504-210-3539
[email protected]

Principal Investigator
Scott E. Delacroix

Facility: Trinity Health Saint Joseph Mercy Hospital Ann Arbor
Ann Arbor, Michigan 48106
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-7251
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Trinity Health IHA Medical Group Hematology Oncology - Brighton
Brighton, Michigan 48114
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-7251
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Trinity Health Medical Center - Brighton
Brighton, Michigan 48114
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-7251
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Trinity Health IHA Medical Group Hematology Oncology - Canton
Canton, Michigan 48188
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-7251
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Trinity Health Medical Center - Canton
Canton, Michigan 48188
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-7251
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Caro Cancer Center
Caro, Michigan 48723
United States
Status: Recruiting Contact: Contact
Site Public Contact
989-907-8411
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Chelsea Hospital
Chelsea, Michigan 48118
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-7251
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
Chelsea, Michigan 48118
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-7251
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Henry Ford Health Saint John Hospital
Detroit, Michigan 48236
United States
Status: Recruiting Contact: Contact
Site Public Contact
313-343-3166
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Genesys Hurley Cancer Institute
Flint, Michigan 48503
United States
Status: Recruiting Contact: Contact
Site Public Contact
810-762-8038
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Hurley Medical Center
Flint, Michigan 48503
United States
Status: Recruiting Contact: Contact
Site Public Contact
810-762-8038
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
Grosse Pointe Woods, Michigan 48236
United States
Status: Recruiting Contact: Contact
Site Public Contact
313-343-3166
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: University of Michigan Health - Sparrow Lansing
Lansing, Michigan 48912
United States
Status: Recruiting Contact: Contact
Site Public Contact
517-364-3712
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Trinity Health Saint Mary Mercy Livonia Hospital
Livonia, Michigan 48154
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-7251
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Great Lakes Cancer Management Specialists-Macomb Medical Campus
Macomb, Michigan 48044
United States
Status: Recruiting Contact: Contact
Site Public Contact
313-343-3166
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Saint Mary's Oncology/Hematology Associates of Marlette
Marlette, Michigan 48453
United States
Status: Recruiting Contact: Contact
Site Public Contact
989-907-8411
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Michigan Healthcare Professionals Pontiac
Pontiac, Michigan 48341
United States
Status: Recruiting Contact: Contact
Site Public Contact
248-858-6215
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Trinity Health Saint Joseph Mercy Oakland Hospital
Pontiac, Michigan 48341
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-7251
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: MyMichigan Medical Center Saginaw
Saginaw, Michigan 48601
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-7251
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Oncology Hematology Associates of Saginaw Valley PC
Saginaw, Michigan 48604
United States
Status: Recruiting Contact: Contact
Site Public Contact
989-907-8411
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: MyMichigan Medical Center Tawas
Tawas City, Michigan 48764
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-7251
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Saint John Macomb-Oakland Hospital
Warren, Michigan 48093
United States
Status: Recruiting Contact: Contact
Site Public Contact
313-343-3166
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Saint Mary's Oncology/Hematology Associates of West Branch
West Branch, Michigan 48661
United States
Status: Recruiting Contact: Contact
Site Public Contact
989-907-8411
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
Ypsilanti, Michigan 48197
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-7251
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Sanford Joe Lueken Cancer Center
Bemidji, Minnesota 56601
United States
Status: Recruiting Contact: Contact
Site Public Contact
218-333-5000
[email protected]

Principal Investigator
Daniel Almquist

Facility: Essentia Health Saint Joseph's Medical Center
Brainerd, Minnesota 56401
United States
Status: Recruiting Contact: Contact
Site Public Contact
218-786-3308
[email protected]

Principal Investigator
Bret E. Friday

Facility: Minnesota Oncology - Burnsville
Burnsville, Minnesota 55337
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: Mercy Hospital
Coon Rapids, Minnesota 55433
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: Essentia Health - Deer River Clinic
Deer River, Minnesota 56636
United States
Status: Recruiting Contact: Contact
Site Public Contact
218-786-3308
[email protected]

Principal Investigator
Bret E. Friday

Facility: Essentia Health Saint Mary's - Detroit Lakes Clinic
Detroit Lakes, Minnesota 56501
United States
Status: Recruiting Contact: Contact
Site Public Contact
218-786-3308
[email protected]

Principal Investigator
Bret E. Friday

Facility: Essentia Health Cancer Center
Duluth, Minnesota 55805
United States
Status: Recruiting Contact: Contact
Site Public Contact
218-786-3308
[email protected]

Principal Investigator
Bret E. Friday

Facility: Essentia Health Saint Mary's Medical Center
Duluth, Minnesota 55805
United States
Status: Recruiting Contact: Contact
Site Public Contact
218-786-3308
[email protected]

Principal Investigator
Bret E. Friday

Facility: Miller-Dwan Hospital
Duluth, Minnesota 55805
United States
Status: Recruiting Contact: Contact
Site Public Contact
218-786-3308
[email protected]

Principal Investigator
Bret E. Friday

Facility: Fairview Southdale Hospital
Edina, Minnesota 55435
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: Essentia Health - Fosston
Fosston, Minnesota 56542
United States
Status: Recruiting Contact: Contact
Site Public Contact
218-786-3308
[email protected]

Principal Investigator
Bret E. Friday

Facility: Essentia Health Hibbing Clinic
Hibbing, Minnesota 55746
United States
Status: Recruiting Contact: Contact
Site Public Contact
218-786-3308

Principal Investigator
Bret E. Friday

Facility: Fairview Clinics and Surgery Center Maple Grove
Maple Grove, Minnesota 55369
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: Minnesota Oncology Hematology PA-Maplewood
Maplewood, Minnesota 55109
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: Saint John's Hospital - Healtheast
Maplewood, Minnesota 55109
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: Abbott-Northwestern Hospital
Minneapolis, Minnesota 55407
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: Hennepin County Medical Center
Minneapolis, Minnesota 55415
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: Health Partners Inc
Minneapolis, Minnesota 55454
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: Monticello Cancer Center
Monticello, Minnesota 55362
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: Essentia Health - Park Rapids
Park Rapids, Minnesota 56470
United States
Status: Recruiting Contact: Contact
Site Public Contact
218-786-3308
[email protected]

Principal Investigator
Bret E. Friday

Facility: North Memorial Medical Health Center
Robbinsdale, Minnesota 55422
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: Coborn Cancer Center at Saint Cloud Hospital
Saint Cloud, Minnesota 56303
United States
Status: Recruiting Contact: Contact
Site Public Contact
877-229-4907
[email protected]

Principal Investigator
Donald J. Jurgens

Facility: Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota 55416
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: Regions Hospital
Saint Paul, Minnesota 55101
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: United Hospital
Saint Paul, Minnesota 55102
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: Essentia Health Sandstone
Sandstone, Minnesota 55072
United States
Status: Recruiting Contact: Contact
Site Public Contact
218-786-3308
[email protected]

Principal Investigator
Bret E. Friday

Facility: Saint Francis Regional Medical Center
Shakopee, Minnesota 55379
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: Lakeview Hospital
Stillwater, Minnesota 55082
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: Essentia Health Virginia Clinic
Virginia, Minnesota 55792
United States
Status: Recruiting Contact: Contact
Site Public Contact
218-786-3308
[email protected]

Principal Investigator
Bret E. Friday

Facility: Ridgeview Medical Center
Waconia, Minnesota 55387
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: Rice Memorial Hospital
Willmar, Minnesota 56201
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: Minnesota Oncology Hematology PA-Woodbury
Woodbury, Minnesota 55125
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: Central Care Cancer Center - Bolivar
Bolivar, Missouri 65613
United States
Status: Recruiting Contact: Contact
Site Public Contact
913-948-5588
[email protected]

Principal Investigator
Jay W. Carlson

Facility: Saint Francis Medical Center
Cape Girardeau, Missouri 63703
United States
Status: Recruiting Contact: Contact
Site Public Contact
573-334-2230
[email protected]

Principal Investigator
Bryan A. Faller

Facility: Southeast Cancer Center
Cape Girardeau, Missouri 63703
United States
Status: Recruiting Contact: Contact
Site Public Contact
573-651-5550

Principal Investigator
Jay W. Carlson

Facility: MU Health - University Hospital/Ellis Fischel Cancer Center
Columbia, Missouri 65212
United States
Status: Recruiting Contact: Contact
Site Public Contact
573-882-7440

Principal Investigator
Kushal Naha

Facility: Siteman Cancer Center at West County Hospital
Creve Coeur, Missouri 63141
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-600-3606
[email protected]

Principal Investigator
Eric M. Knoche

Facility: Parkland Health Center - Farmington
Farmington, Missouri 63640
United States
Status: Recruiting Contact: Contact
Site Public Contact
314-996-5569

Principal Investigator
Bryan A. Faller

Facility: MU Health Care Goldschmidt Cancer Center
Jefferson City, Missouri 65109
United States
Status: Recruiting Contact: Contact
Site Public Contact
573-632-4851
[email protected]

Principal Investigator
Kushal Naha

Facility: Freeman Health System
Joplin, Missouri 64804
United States
Status: Recruiting Contact: Contact
Site Public Contact
417-347-4030
[email protected]

Principal Investigator
Jay W. Carlson

Facility: Mercy Hospital Joplin
Joplin, Missouri 64804
United States
Status: Recruiting Contact: Contact
Site Public Contact
417-556-3074
[email protected]

Principal Investigator
Jay W. Carlson

Facility: Delbert Day Cancer Institute at PCRMC
Rolla, Missouri 65401
United States
Status: Recruiting Contact: Contact
Site Public Contact
573-458-7504
[email protected]

Principal Investigator
Jay W. Carlson

Facility: Mercy Clinic-Rolla-Cancer and Hematology
Rolla, Missouri 65401
United States
Status: Recruiting Contact: Contact
Site Public Contact
573-458-6379

Principal Investigator
Jay W. Carlson

Facility: Heartland Regional Medical Center
Saint Joseph, Missouri 64506
United States
Status: Recruiting Contact: Contact
Site Public Contact
816-271-7937
[email protected]

Principal Investigator
Jay W. Carlson

Facility: Washington University School of Medicine
Saint Louis, Missouri 63110
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-600-3606
[email protected]

Principal Investigator
Eric M. Knoche

Facility: Mercy Hospital South
Saint Louis, Missouri 63128
United States
Status: Recruiting Contact: Contact
Site Public Contact
314-525-6042
[email protected]

Principal Investigator
Jay W. Carlson

Facility: Siteman Cancer Center-South County
Saint Louis, Missouri 63129
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-600-3606
[email protected]

Principal Investigator
Eric M. Knoche

Facility: Missouri Baptist Medical Center
Saint Louis, Missouri 63131
United States
Status: Recruiting Contact: Contact
Site Public Contact
314-996-5569

Principal Investigator
Bryan A. Faller

Facility: Siteman Cancer Center at Christian Hospital
Saint Louis, Missouri 63136
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-600-3606
[email protected]

Principal Investigator
Eric M. Knoche

Facility: Mercy Hospital Saint Louis
Saint Louis, Missouri 63141
United States
Status: Recruiting Contact: Contact
Site Public Contact
314-251-7066

Principal Investigator
Jay W. Carlson

Facility: Sainte Genevieve County Memorial Hospital
Sainte Genevieve, Missouri 63670
United States
Status: Recruiting Contact: Contact
Site Public Contact
314-996-5569

Principal Investigator
Bryan A. Faller

Facility: Mercy Hospital Springfield
Springfield, Missouri 65804
United States
Status: Recruiting Contact: Contact
Site Public Contact
417-269-4520

Principal Investigator
Jay W. Carlson

Facility: CoxHealth South Hospital
Springfield, Missouri 65807
United States
Status: Recruiting Contact: Contact
Site Public Contact
417-269-4520

Principal Investigator
Jay W. Carlson

Facility: Missouri Baptist Sullivan Hospital
Sullivan, Missouri 63080
United States
Status: Recruiting Contact: Contact
Site Public Contact
314-996-5569

Principal Investigator
Bryan A. Faller

Facility: BJC Outpatient Center at Sunset Hills
Sunset Hills, Missouri 63127
United States
Status: Recruiting Contact: Contact
Site Public Contact
314-996-5569

Principal Investigator
Bryan A. Faller

Facility: Billings Clinic Cancer Center
Billings, Montana 59101
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-996-2663
[email protected]

Principal Investigator
John M. Schallenkamp

Facility: Bozeman Health Deaconess Hospital
Bozeman, Montana 59715
United States
Status: Recruiting Contact: Contact
Site Public Contact
406-969-6060
[email protected]

Principal Investigator
John M. Schallenkamp

Facility: Benefis Sletten Cancer Institute
Great Falls, Montana 59405
United States
Status: Recruiting Contact: Contact
Site Public Contact
406-969-6060
[email protected]

Principal Investigator
John M. Schallenkamp

Facility: Great Falls Clinic
Great Falls, Montana 59405
United States
Status: Recruiting Contact: Contact
Site Public Contact
406-969-6060
[email protected]

Principal Investigator
John M. Schallenkamp

Facility: Kalispell Regional Medical Center
Kalispell, Montana 59901
United States
Status: Recruiting Contact: Contact
Site Public Contact
406-969-6060
[email protected]

Principal Investigator
John M. Schallenkamp

Facility: Community Medical Center
Missoula, Montana 59804
United States
Status: Recruiting Contact: Contact
Site Public Contact
406-969-6060
[email protected]

Principal Investigator
John M. Schallenkamp

Facility: CHI Health Good Samaritan
Kearney, Nebraska 68847
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Alegent Health Immanuel Medical Center
Omaha, Nebraska 68122
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Alegent Health Bergan Mercy Medical Center
Omaha, Nebraska 68124
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Alegent Health Lakeside Hospital
Omaha, Nebraska 68130
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Creighton University Medical Center
Omaha, Nebraska 68131
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Memorial Sloan Kettering Basking Ridge
Basking Ridge, New Jersey 07920
United States
Status: Recruiting Contact: Contact
Site Public Contact
212-639-7592

Principal Investigator
Gopakumar V. Iyer

Facility: Englewood Hospital and Medical Center
Englewood, New Jersey 07631
United States
Status: Recruiting Contact: Contact
Site Public Contact
201-894-3456

Principal Investigator
Brian H. Kim

Facility: Memorial Sloan Kettering Monmouth
Middletown, New Jersey 07748
United States
Status: Recruiting Contact: Contact
Site Public Contact
212-639-7592

Principal Investigator
Gopakumar V. Iyer

Facility: Memorial Sloan Kettering Bergen
Montvale, New Jersey 07645
United States
Status: Recruiting Contact: Contact
Site Public Contact
212-639-7592

Principal Investigator
Gopakumar V. Iyer

Facility: Memorial Sloan Kettering Commack
Commack, New York 11725
United States
Status: Recruiting Contact: Contact
Site Public Contact
212-639-7592

Principal Investigator
Gopakumar V. Iyer

Facility: Memorial Sloan Kettering Westchester
Harrison, New York 10604
United States
Status: Recruiting Contact: Contact
Site Public Contact
212-639-7592

Principal Investigator
Gopakumar V. Iyer

Facility: Laura and Isaac Perlmutter Cancer Center at NYU Langone
New York, New York 10016
United States
Status: Recruiting Contact: Contact
Site Public Contact
[email protected]

Principal Investigator
Katie S. Murray

Facility: Memorial Sloan Kettering Cancer Center
New York, New York 10065
United States
Status: Recruiting Contact: Contact
Site Public Contact
212-639-7592

Principal Investigator
Gopakumar V. Iyer

Facility: NYP/Weill Cornell Medical Center
New York, New York 10065
United States
Status: Recruiting Contact: Contact
Site Public Contact
212-746-1848

Principal Investigator
Bishoy Faltas

Facility: Upstate Cancer Center at Oswego
Oswego, New York 13126
United States
Status: Recruiting Contact: Contact
Site Public Contact
315-464-8230
[email protected]

Principal Investigator
Alina Basnet

Facility: University of Rochester
Rochester, New York 14642
United States
Status: Recruiting Contact: Contact
Site Public Contact
585-275-5830

Principal Investigator
Paul M. Barr

Facility: State University of New York Upstate Medical University
Syracuse, New York 13210
United States
Status: Recruiting Contact: Contact
Site Public Contact
315-464-5476

Principal Investigator
Alina Basnet

Facility: Memorial Sloan Kettering Nassau
Uniondale, New York 11553
United States
Status: Recruiting Contact: Contact
Site Public Contact
212-639-7592

Principal Investigator
Gopakumar V. Iyer

Facility: Upstate Cancer Center at Verona
Verona, New York 13478
United States
Status: Recruiting Contact: Contact
Site Public Contact
315-464-8230
[email protected]

Principal Investigator
Alina Basnet

Facility: Sanford Bismarck Medical Center
Bismarck, North Dakota 58501
United States
Status: Recruiting Contact: Contact
Site Public Contact
701-323-5760
[email protected]

Principal Investigator
Daniel Almquist

Facility: Essentia Health Cancer Center-South University Clinic
Fargo, North Dakota 58103
United States
Status: Recruiting Contact: Contact
Site Public Contact
218-786-3308
[email protected]

Principal Investigator
Bret E. Friday

Facility: Sanford Broadway Medical Center
Fargo, North Dakota 58122
United States
Status: Recruiting Contact: Contact
Site Public Contact
701-323-5760
[email protected]

Principal Investigator
Daniel Almquist

Facility: Sanford Roger Maris Cancer Center
Fargo, North Dakota 58122
United States
Status: Recruiting Contact: Contact
Site Public Contact
701-234-6161
[email protected]

Principal Investigator
Daniel Almquist

Facility: Essentia Health - Jamestown Clinic
Jamestown, North Dakota 58401
United States
Status: Recruiting Contact: Contact
Site Public Contact
218-786-3308
[email protected]

Principal Investigator
Bret E. Friday

Facility: Indu and Raj Soin Medical Center
Beavercreek, Ohio 45431
United States
Status: Recruiting Contact: Contact
Site Public Contact
937-528-2900
[email protected]

Principal Investigator
Howard M. Gross

Facility: Saint Elizabeth Boardman Hospital
Boardman, Ohio 44512
United States
Status: Recruiting Contact: Contact
Site Public Contact
937-528-2900
[email protected]

Principal Investigator
Howard M. Gross

Facility: Dayton Physicians LLC-Miami Valley South
Centerville, Ohio 45459
United States
Status: Recruiting Contact: Contact
Site Public Contact
937-528-2900
[email protected]

Principal Investigator
Howard M. Gross

Facility: Good Samaritan Hospital - Cincinnati
Cincinnati, Ohio 45220
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Oncology Hematology Care Inc-Kenwood
Cincinnati, Ohio 45236
United States
Status: Recruiting Contact: Contact
Site Public Contact
937-528-2900
[email protected]

Principal Investigator
Howard M. Gross

Facility: Bethesda North Hospital
Cincinnati, Ohio 45242
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Cleveland Clinic Foundation
Cleveland, Ohio 44195
United States
Status: Recruiting Contact: Contact
Site Public Contact
866-223-8100
[email protected]

Principal Investigator
Shilpa Gupta

Facility: Ohio State University Comprehensive Cancer Center
Columbus, Ohio 43210
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-293-5066
[email protected]

Principal Investigator
Amir Mortazavi

Facility: Dayton Physician LLC - Englewood
Dayton, Ohio 45415
United States
Status: Recruiting Contact: Contact
Site Public Contact
937-528-2900
[email protected]

Principal Investigator
Howard M. Gross

Facility: Armes Family Cancer Center
Findlay, Ohio 45840
United States
Status: Recruiting Contact: Contact
Site Public Contact
937-528-2900
[email protected]

Principal Investigator
Howard M. Gross

Facility: Blanchard Valley Hospital
Findlay, Ohio 45840
United States
Status: Recruiting Contact: Contact
Site Public Contact
937-528-2900
[email protected]

Principal Investigator
Howard M. Gross

Facility: Orion Cancer Care
Findlay, Ohio 45840
United States
Status: Recruiting Contact: Contact
Site Public Contact
937-528-2900
[email protected]

Principal Investigator
Howard M. Gross

Facility: Dayton Physicians LLC-Atrium
Franklin, Ohio 45005
United States
Status: Recruiting Contact: Contact
Site Public Contact
937-528-2900
[email protected]

Principal Investigator
Howard M. Gross

Facility: Dayton Physicians LLC-Wayne
Greenville, Ohio 45331
United States
Status: Recruiting Contact: Contact
Site Public Contact
937-528-2900
[email protected]

Principal Investigator
Howard M. Gross

Facility: Wayne Hospital
Greenville, Ohio 45331
United States
Status: Recruiting Contact: Contact
Site Public Contact
937-528-2900
[email protected]

Principal Investigator
Howard M. Gross

Facility: Greater Dayton Cancer Center
Kettering, Ohio 45409
United States
Status: Recruiting Contact: Contact
Site Public Contact
937-528-2900
[email protected]

Principal Investigator
Howard M. Gross

Facility: Kettering Medical Center
Kettering, Ohio 45429
United States
Status: Recruiting Contact: Contact
Site Public Contact
937-528-2900
[email protected]

Principal Investigator
Howard M. Gross

Facility: Dayton Physicians LLC - Troy
Troy, Ohio 45373
United States
Status: Recruiting Contact: Contact
Site Public Contact
937-528-2900
[email protected]

Principal Investigator
Howard M. Gross

Facility: Saint Joseph Warren Hospital
Warren, Ohio 44484
United States
Status: Recruiting Contact: Contact
Site Public Contact
937-528-2900
[email protected]

Principal Investigator
Howard M. Gross

Facility: Saint Elizabeth Youngstown Hospital
Youngstown, Ohio 44501
United States
Status: Recruiting Contact: Contact
Site Public Contact
937-528-2900
[email protected]

Principal Investigator
Howard M. Gross

Facility: University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma 73104
United States
Status: Recruiting Contact: Contact
Site Public Contact
405-271-8777
[email protected]

Principal Investigator
Adanma Anji Ayanambakkam Attanathi

Facility: Mercy Hospital Oklahoma City
Oklahoma City, Oklahoma 73120
United States
Status: Recruiting Contact: Contact
Site Public Contact
405-752-3402

Principal Investigator
Jay W. Carlson

Facility: Lehigh Valley Hospital-Cedar Crest
Allentown, Pennsylvania 18103
United States
Status: Recruiting Contact: Contact
Site Public Contact
610-402-9543
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Lehigh Valley Hospital - Muhlenberg
Bethlehem, Pennsylvania 18017
United States
Status: Recruiting Contact: Contact
Site Public Contact
610-402-9543
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Geisinger Medical Center
Danville, Pennsylvania 17822
United States
Status: Recruiting Contact: Contact
Site Public Contact
570-271-5251
[email protected]

Principal Investigator
Ahmad Hanif

Facility: Pocono Medical Center
East Stroudsburg, Pennsylvania 18301
United States
Status: Recruiting Contact: Contact
Site Public Contact
610-402-9543
[email protected]

Principal Investigator
Tareq Al baghdadi

Facility: Geisinger Medical Center-Cancer Center Hazleton
Hazleton, Pennsylvania 18201
United States
Status: Recruiting Contact: Contact
Site Public Contact
570-459-2901
[email protected]

Principal Investigator
Ahmad Hanif

Facility: Geisinger Medical Oncology-Lewisburg
Lewisburg, Pennsylvania 17837
United States
Status: Recruiting Contact: Contact
Site Public Contact
570-374-8555
[email protected]

Principal Investigator
Ahmad Hanif

Facility: Lewistown Hospital
Lewistown, Pennsylvania 17044
United States
Status: Recruiting Contact: Contact
Site Public Contact
717-242-7703
[email protected]

Principal Investigator
Ahmad Hanif

Facility: Geisinger Cancer Services-Pottsville
Pottsville, Pennsylvania 17901
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-275-6401
[email protected]

Principal Investigator
Ahmad Hanif

Facility: Community Medical Center
Scranton, Pennsylvania 18510
United States
Status: Recruiting Contact: Contact
Site Public Contact
570-703-4768
[email protected]

Principal Investigator
Ahmad Hanif

Facility: Geisinger Medical Oncology-Selinsgrove
Selinsgrove, Pennsylvania 17870
United States
Status: Recruiting Contact: Contact
Site Public Contact
570-374-8555
[email protected]

Principal Investigator
Ahmad Hanif

Facility: Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-Barre, Pennsylvania 18711
United States
Status: Recruiting Contact: Contact
Site Public Contact
570-271-5251
[email protected]

Principal Investigator
Ahmad Hanif

Facility: Rhode Island Hospital
Providence, Rhode Island 02903
United States
Status: Recruiting Contact: Contact
Site Public Contact
401-444-1488

Principal Investigator
Galina Lagos

Facility: Gibbs Cancer Center-Gaffney
Gaffney, South Carolina 29341
United States
Status: Recruiting Contact: Contact
Site Public Contact
864-560-6104
[email protected]

Principal Investigator
Michael Humeniuk

Facility: Gibbs Cancer Center-Pelham
Greer, South Carolina 29651
United States
Status: Recruiting Contact: Contact
Site Public Contact
864-560-6104
[email protected]

Principal Investigator
Michael Humeniuk

Facility: Spartanburg Medical Center
Spartanburg, South Carolina 29303
United States
Status: Recruiting Contact: Contact
Site Public Contact
864-560-6104
[email protected]

Principal Investigator
Michael Humeniuk

Facility: MGC Hematology Oncology-Union
Union, South Carolina 29379
United States
Status: Recruiting Contact: Contact
Site Public Contact
864-560-6104
[email protected]

Principal Investigator
Michael Humeniuk

Facility: Sanford Cancer Center Oncology Clinic
Sioux Falls, South Dakota 57104
United States
Status: Recruiting Contact: Contact
Site Public Contact
605-312-3320
[email protected]

Principal Investigator
Daniel Almquist

Facility: Sanford USD Medical Center - Sioux Falls
Sioux Falls, South Dakota 57117-5134
United States
Status: Recruiting Contact: Contact
Site Public Contact
605-312-3320
[email protected]

Principal Investigator
Daniel Almquist

Facility: Harrison HealthPartners Hematology and Oncology-Bremerton
Bremerton, Washington 98310
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
[email protected]

Principal Investigator
Richard L. Deming

Facility: Saint Michael Cancer Center
Silverdale, Washington 98383
United States
Status: Recruiting Contact: Contact
Site Public Contact
720-874-1881
[email protected]

Principal Investigator
Shahzad Siddique

Facility: Langlade Hospital and Cancer Center
Antigo, Wisconsin 54409
United States
Status: Recruiting Contact: Contact
Site Public Contact
715-623-9869
[email protected]

Principal Investigator
Andrew J. Huang

Facility: Duluth Clinic Ashland
Ashland, Wisconsin 54806
United States
Status: Recruiting Contact: Contact
Site Public Contact
218-786-3308
[email protected]

Principal Investigator
Bret E. Friday

Facility: Northwest Wisconsin Cancer Center
Ashland, Wisconsin 54806
United States
Status: Recruiting Contact: Contact
Site Public Contact
218-786-3308
[email protected]

Principal Investigator
Bret E. Friday

Facility: Marshfield Medical Center-EC Cancer Center
Eau Claire, Wisconsin 54701
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-782-8581
[email protected]

Principal Investigator
Dean A. Delmastro

Facility: Essentia Health-Hayward Clinic
Hayward, Wisconsin 54843
United States
Status: Recruiting Contact: Contact
Site Public Contact
218-786-3308
[email protected]

Principal Investigator
Bret E. Friday

Facility: Gundersen Lutheran Medical Center
La Crosse, Wisconsin 54601
United States
Status: Recruiting Contact: Contact
Site Public Contact
608-775-2385
[email protected]

Principal Investigator
Michael O. Ojelabi

Facility: Marshfield Medical Center - Ladysmith
Ladysmith, Wisconsin 54848
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-782-8581
[email protected]

Principal Investigator
Dean A. Delmastro

Facility: Marshfield Medical Center-Marshfield
Marshfield, Wisconsin 54449
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-782-8581
[email protected]

Principal Investigator
Dean A. Delmastro

Facility: Aspirus Medford Hospital
Medford, Wisconsin 54451
United States
Status: Recruiting Contact: Contact
Site Public Contact
715-847-2353
[email protected]

Principal Investigator
Andrew J. Huang

Facility: Marshfield Clinic-Minocqua Center
Minocqua, Wisconsin 54548
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-782-8581
[email protected]

Principal Investigator
Dean A. Delmastro

Facility: Cancer Center of Western Wisconsin
New Richmond, Wisconsin 54017
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
[email protected]

Principal Investigator
Daniel M. Anderson

Facility: Ascension Saint Mary's Hospital
Rhinelander, Wisconsin 54501
United States
Status: Recruiting Contact: Contact
Site Public Contact
715-847-2353
[email protected]

Principal Investigator
Andrew J. Huang

Facility: Marshfield Medical Center-Rice Lake
Rice Lake, Wisconsin 54868
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-782-8581
[email protected]

Principal Investigator
Dean A. Delmastro

Facility: Essentia Health-Spooner Clinic
Spooner, Wisconsin 54801
United States
Status: Recruiting Contact: Contact
Site Public Contact
218-786-3308
[email protected]

Principal Investigator
Bret E. Friday

Facility: Ascension Saint Michael's Hospital
Stevens Point, Wisconsin 54481
United States
Status: Recruiting Contact: Contact
Site Public Contact
715-847-2353
[email protected]

Principal Investigator
Andrew J. Huang

Facility: Marshfield Medical Center-River Region at Stevens Point
Stevens Point, Wisconsin 54482
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-782-8581
[email protected]

Principal Investigator
Dean A. Delmastro

Facility: Essentia Health Saint Mary's Hospital - Superior
Superior, Wisconsin 54880
United States
Status: Recruiting Contact: Contact
Site Public Contact
701-364-6272

Principal Investigator
Bret E. Friday

Facility: Aspirus Regional Cancer Center
Wausau, Wisconsin 54401
United States
Status: Recruiting Contact: Contact
Site Public Contact
877-405-6866

Principal Investigator
Andrew J. Huang

Facility: Diagnostic and Treatment Center
Weston, Wisconsin 54476
United States
Status: Recruiting Contact: Contact
Site Public Contact
888-799-3989
[email protected]

Principal Investigator
Dean A. Delmastro

Facility: Marshfield Medical Center - Weston
Weston, Wisconsin 54476
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-782-8581
[email protected]

Principal Investigator
Dean A. Delmastro

Facility: Aspirus Cancer Care - Wisconsin Rapids
Wisconsin Rapids, Wisconsin 54494
United States
Status: Recruiting Contact: Contact
Site Public Contact
715-422-7718

Principal Investigator
Andrew J. Huang

Facility: Welch Cancer Center
Sheridan, Wyoming 82801
United States
Status: Recruiting Contact: Contact
Site Public Contact
406-969-6060
[email protected]

Principal Investigator
John M. Schallenkamp