Brief Title: mpMRI Compared to Diagnostic TURBT in Patients With Suspected Muscle-Invasive Bladder Cancer

PRIMARY OUTCOMES

Primary Outcome 1 - Measure:

Primary Outcome 1 - Timeframe: N/A

CONDITION

• Urothelial Bladder Cancer
• Muscle-Invasive Bladder Cancer

ELIGIBILITY

Inclusion Criteria:
* Age 18 years old or greater at the time of consent.

- * Suspected muscle-invasive bladder cancer by tumor appearance on initial routine cystoscopy as determined by the UCI-affiliated urologist performing this procedure.

- * ECOG Performance Status of 0-3.

- * Patients must have the ability to understand and the willingness to sign a written informed consent document (prior to the initiation of the study and any study procedures).

- * Patients must be willing and able to comply with the scheduled visits, imaging plan, follow up plan, and other specified study procedures in the opinion of the Investigator.
Exclusion Criteria:
* Prior TURBT within 120 days of study entry.

- * Prior therapy for bladder cancer within 120 days of study entry.

- * Inability to tolerate mpMRI or associated contrast.

- * Inability to tolerate TURBT or associated anesthesia.

- * ECOG Performance Status of 4.

- * Female patient who is known to be pregnant or breastfeeding.

Gender: All

Minimum Age: 18 Years

Maximum Age: N/A

Healthy Volunteers: No

OFFICIAL INFORMATION

Name: Nataliya Mar, MD

Role: Principal Investigator

Affiliation: Chao Family Comprehensive Cancer Center

Overall Contact

Name: Chao Family Comprehensive Cancer Center University of California, Irvine, University of California Irvine Medical

Phone: 1-877-827-8839

Email: ucstudy@uci.edu, marn@hs.uci.edu

LOCATION