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Brief Title: Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy

Duration of Immune Checkpoint Therapy in Locally Advanced or Metastatic Urothelial Carcinoma: A Randomized Phase 3 Non-Inferiority Trial

INTRODUCTION

  • Org Study ID: A031901
  • Secondary ID: NCI-2020-08395, U10CA180821
  • NTC ID: NCT04637594
  • Sponsor: Alliance for Clinical Trials in Oncology

BRIEF SUMMARY

This phase III trial compares survival in urothelial cancer patients who stop immune checkpoint inhibitor treatment after being treated for about a year to those patients who continue treatment with immune checkpoint inhibitors. Immunotherapy with monoclonal antibodies, such as avelumab, durvalumab, pembrolizumab, atezolizumab, and nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Stopping immune checkpoint inhibitors early may still make the tumor shrink and patients may have similar survival rates as the patients who continue treatment. Stopping treatment early may also lead to fewer treatment-related side effects, an improvement in mental health, and a lower cost burden to patients.

DETAILED DESCRIPTION

PRIMARY OBJECTIVE:

I. To compare overall survival (OS).

SECONDARY OBJECTIVES:

I. To compare progression free survival (PFS) by (Response Evaluation Criteria in Solid Tumors) RECIST 1.1 criteria.

II. To compare PFS by immune-related (ir)RECIST criteria. III. To determine treatment-free interval (TFI) after immune checkpoint inhibitor (ICI) discontinuation. (Arm B) IV. To determine the rate of response by RECIST 1.1 criteria after ICI rechallenge. (Arm B) V. To assess adverse events in each study arm by Common Terminology Criteria for Adverse Events (CTCAE) 5.0.

OUTLINE: Patient are randomized to 1 of 2 arms.

ARM A (CONTINUATION OF ICI TREATMENT): Patients receive either pembrolizumab intravenously (IV) over 30 minutes on day 1, nivolumab IV over 30 minutes on days 1 and 15, atezolizumab IV over 30-60 minutes on day 1, durvalumab IV over 60 minutes on days 1 and 15, or avelumab IV over 60 minutes on days 1 and 15. Cycles repeat every 21 or 42 days for pembrolizumab, every 21 days for atezolizumab, and 28 days for nivolumab, durvalumab, and avelumab in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, starting new treatment or withdrawn consent, patients are followed up at 4 weeks, and then every 6 months for 5 years following registration.

ARM B (DISCONTINUATION OF ICI TREATMENT): Patients receiving ICI treatment will discontinue ICI treatment within 1 cycle length after randomization. Cycle length is determined by the ICI regimen the patient is receiving at randomization. At disease progression patients may restart the same ICI treatment they were receiving upon randomization at physician discretion.

After initiation of new treatment (after ICI rechallenge or without ICI rechallenge), or progression (after ICI rechallenge or without ICI rechallenge), patients are followed up at 4 weeks, and then every 6 months for 5 years following registration.

  • Overall Status
    Recruiting
  • Start Date
    December 10, 2020
  • Phase
    Phase 3
  • Study Type
    Interventional

PRIMARY OUTCOMES

Primary Outcome 1 - Measure: Overall survival (OS)

Primary Outcome 1 - Timeframe: From randomization until death due to any cause, assessed up to 5 years

CONDITION

  • Locally Advanced Bladder Urothelial Carcinoma
  • Locally Advanced Renal Pelvis Urothelial Carcinoma
  • Locally Advanced Ureter Urothelial Carcinoma
  • Locally Advanced Urethral Urothelial Carcinoma
  • Locally Advanced Urothelial Carcinoma
  • Metastatic Bladder Urothelial Carcinoma
  • Metastatic Renal Pelvis Urothelial Carcinoma
  • Metastatic Ureter Urothelial Carcinoma
  • Metastatic Urethral Urothelial Carcinoma
  • Metastatic Urothelial Carcinoma

ELIGIBILITY

Inclusion Criteria:
Documentation of disease
Histologic documentation: Histologically or cytologically confirmed urothelial carcinoma (UC) with predominantly transitional-cell features

- Stage: Locally advanced or metastatic disease prior to starting immune checkpoint blockade

- Tumor Site: Bladder, renal pelvis, ureter, or urethra

- Patients must be receiving current active treatment with standard of care (SOC) Food and Drug Administration (FDA) approved PD-1/L1 immune checkpoint inhibitor (ICI)-containing therapy for locally advance or metastatic UC

- Radiographic response 12-15 months after starting ICI-containing treatment, defined as any percent decrease in target and/or non-target lesion(s) criteria that is confirmed by repeat assessment(s) no less than 4 weeks after the criteria for response are first met without evidence of progressive disease

- Adequate bone marrow and organ functions to continue PD-1/L1 ICI as judged by the treating physician

- Eastern Cooperative Oncology Group (ECOG) performance status 0-2

- Central nervous system (CNS) metastasis is allowed if radiographically stable, clinically asymptomatic, and prior local therapy (if received) was completed > 6 months before registration
Exclusion Criteria:
No toxicity from ICI therapy that makes continuation of treatment clinically unacceptable
No history of tuberculosis, active hepatitis B (HBV) or hepatitis C (HCV), or uncontrolled human immunodeficiency virus (HIV)
Patients with resolved HBV infection, defined as positive hepatitis B core antibody (anti-Hb) and negative hepatitis B surface antigen (HbsAg), are eligible

- Patients with positive HCV antibody are eligible if HCV ribonucleic acid (RNA) polymerase chain reaction (PCR) is negative

- Patients with HIV who are compliant with highly active antiretroviral therapy (HAART) and have normal CD4 count and undetectable viral load are eligible

- No history of allogeneic organ transplantation
No current immunosuppressive medication exceeding 10 mg/day of prednisone or its equivalent
* Patients with pre-existing or treatment-emergent autoimmune or inflammatory disorders which do not require systemic immunosuppressive treatment exceeding 10 mg/day of prednisone or its equivalent may be included
No history of another primary malignancy except for malignancy treated with curative intent with no known active disease for >= 2 years, and adequately treated non-melanomatous skin cancer or carcinoma in situ (e.g. cervical carcinoma in situ [CIS]) without evidence of disease

- No female patients who are pregnant or breastfeeding, or male or female patients of reproductive potential who are not willing to employ effective birth control, because this study involves investigational agents whose genotoxic, mutagenic, and teratogenic effects on the developing fetus and newborn are unknown. Therefore, for women of childbearing potential only, a negative urine or serum pregnancy test pregnancy test done =< 14 days prior to registration is required

Gender: All

Minimum Age: 18 Years

Maximum Age: N/A

Healthy Volunteers: No

OFFICIAL INFORMATION

Name: Xiao X. Wei, MD, MAS

Role: Study Chair

Affiliation: Dana-Farber Cancer Institute

Overall Contact

Name: Xiao X. Wei, MD, MAS

Phone: 617-632-4524

Email: xiaox_wei@dfci.harvard.edu

LOCATION

Facility Status Contact
Facility: Anchorage Associates in Radiation Medicine
Anchorage, Alaska 98508
United States
Status: Recruiting Contact: Contact
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org
Facility: Anchorage Radiation Therapy Center
Anchorage, Alaska 99504
United States
Status: Recruiting Contact: Principal Investigator
Alison K. Conlin
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org
Facility: Alaska Breast Care and Surgery LLC
Anchorage, Alaska 99508
United States
Status: Recruiting Contact: Contact
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org
Facility: Alaska Oncology and Hematology LLC
Anchorage, Alaska 99508
United States
Status: Recruiting Contact: Principal Investigator
Alison K. Conlin
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org
Facility: Alaska Women's Cancer Care
Anchorage, Alaska 99508
United States
Status: Recruiting Contact: Contact
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org
Facility: Anchorage Oncology Centre
Anchorage, Alaska 99508
United States
Status: Recruiting Contact: Principal Investigator
Alison K. Conlin
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org
Facility: Katmai Oncology Group
Anchorage, Alaska 99508
United States
Status: Recruiting Contact: Contact
Site Public Contact
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org
Facility: Providence Alaska Medical Center
Anchorage, Alaska 99508
United States
Status: Recruiting Contact: Principal Investigator
Alison K. Conlin
907-212-6871
AKPAMC.OncologyResearchSupport@providence.org
Facility: Mercy Hospital Fort Smith
Fort Smith, Arkansas 72903
United States
Status: Recruiting Contact: Principal Investigator
Alison K. Conlin
308-398-6518
Kpoct@kp.org
Facility: CHI Saint Vincent Cancer Center Hot Springs
Hot Springs, Arkansas 71913
United States
Status: Recruiting Contact: Contact
Site Public Contact
877-642-4691
research@dignityhealth.org
Facility: Kaiser Permanente-Deer Valley Medical Center
Antioch, California 94531
United States
Status: Recruiting Contact: Principal Investigator
Alison K. Conlin
916-851-2283
Najee.Boucher@providence.org
Facility: Mission Hope Medical Oncology - Arroyo Grande
Arroyo Grande, California 93420
United States
Status: Recruiting Contact: Contact
Site Public Contact
818-847-4793
Kpoct@kp.org
Facility: Providence Saint Joseph Medical Center/Disney Family Cancer Center
Burbank, California 91505
United States
Status: Recruiting Contact: Principal Investigator
Alison K. Conlin
877-642-4691
Kpoct@kp.org
Facility: Kaiser Permanente Dublin
Dublin, California 94568
United States
Status: Recruiting Contact: Contact
Site Public Contact
877-642-4691
Kpoct@kp.org
Facility: Kaiser Permanente-Fremont
Fremont, California 94538
United States
Status: Recruiting Contact: Principal Investigator
Alison K. Conlin
877-642-4691
Kpoct@kp.org
Facility: Fresno Cancer Center
Fresno, California 93720
United States
Status: Recruiting Contact: Contact
Site Public Contact
877-642-4691
Kpoct@kp.org
Facility: Kaiser Permanente-Fresno
Fresno, California 93720
United States
Status: Recruiting Contact: Principal Investigator
Jay W. Carlson
877-642-4691
Kpoct@kp.org
Facility: Kaiser Permanente-Modesto
Modesto, California 95356
United States
Status: Recruiting Contact: Contact
Site Public Contact
877-642-4691
Kpoct@kp.org
Facility: Kaiser Permanente Oakland-Broadway
Oakland, California 94611
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
877-642-4691
Kpoct@kp.org
Facility: Kaiser Permanente-Oakland
Oakland, California 94611
United States
Status: Recruiting Contact: Contact
Site Public Contact
877-642-4691
Kpoct@kp.org
Facility: Kaiser Permanente-Rancho Cordova Cancer Center
Rancho Cordova, California 95670
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
877-642-4691
Kpoct@kp.org
Facility: Kaiser Permanente- Marshall Medical Offices
Redwood City, California 94063
United States
Status: Recruiting Contact: Contact
Site Public Contact
877-642-4691
Kpoct@kp.org
Facility: Kaiser Permanente-Richmond
Richmond, California 94801
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
877-642-4691
kpoct@kp.org
Facility: Rohnert Park Cancer Center
Rohnert Park, California 94928
United States
Status: Recruiting Contact: Contact
Site Public Contact
877-642-4691
Kpoct@kp.org
Facility: Kaiser Permanente-Roseville
Roseville, California 95661
United States
Status: Recruiting Contact: Principal Investigator
Alison K. Conlin
877-642-4691
Kpoct@kp.org
Facility: The Permanente Medical Group-Roseville Radiation Oncology
Roseville, California 95678
United States
Status: Recruiting Contact: Contact
Site Public Contact
877-642-4691
Kpoct@kp.org
Facility: Kaiser Permanente Downtown Commons
Sacramento, California 95814
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
877-642-4691
Kpoct@kp.org
Facility: Kaiser Permanente-South Sacramento
Sacramento, California 95823
United States
Status: Recruiting Contact: Contact
Site Public Contact
877-642-4691
Kpoct@kp.org
Facility: South Sacramento Cancer Center
Sacramento, California 95823
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
877-642-4691
Diane.DeVos-Schmidt@DignityHealth.org
Facility: Kaiser Permanente-San Francisco
San Francisco, California 94115
United States
Status: Recruiting Contact: Contact
Site Public Contact
877-642-4691
Kpoct@kp.org
Facility: Kaiser Permanente-Santa Teresa-San Jose
San Jose, California 95119
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
877-642-4691
Kpoct@kp.org
Facility: Kaiser Permanente San Leandro
San Leandro, California 94577
United States
Status: Recruiting Contact: Contact
Site Public Contact
877-642-4691
research@dignityhealth.org
Facility: Pacific Central Coast Health Center-San Luis Obispo
San Luis Obispo, California 93401
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
877-642-4691
Kpoct@kp.org
Facility: Kaiser San Rafael-Gallinas
San Rafael, California 94903
United States
Status: Recruiting Contact: Contact
Site Public Contact
916-851-2283
Kpoct@kp.org
Facility: Kaiser Permanente Medical Center - Santa Clara
Santa Clara, California 95051
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
877-642-4691
Kpoct@kp.org
Facility: Mission Hope Medical Oncology - Santa Maria
Santa Maria, California 93444
United States
Status: Recruiting Contact: Contact
Site Public Contact
877-642-4691
Kpoct@kp.org
Facility: Kaiser Permanente-Santa Rosa
Santa Rosa, California 95403
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
877-642-4691
Kpoct@kp.org
Facility: Kaiser Permanente Cancer Treatment Center
South San Francisco, California 94080
United States
Status: Recruiting Contact: Contact
Site Public Contact
877-642-4691
Kpoct@kp.org
Facility: Kaiser Permanente-South San Francisco
South San Francisco, California 94080
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
877-642-4691
Kpoct@kp.org
Facility: Kaiser Permanente-Stockton
Stockton, California 95210
United States
Status: Recruiting Contact: Contact
Site Public Contact
877-642-4691
clinicaltrials@sfmc-gi.org
Facility: Kaiser Permanente Medical Center-Vacaville
Vacaville, California 95688
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
877-642-4691
info@westernstatesncorp.org
Facility: Kaiser Permanente-Vallejo
Vallejo, California 94589
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org
Facility: Kaiser Permanente-Walnut Creek
Walnut Creek, California 94596
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
303-777-2663
clinicaltrials@sfmc-gi.org
Facility: Penrose-Saint Francis Healthcare
Colorado Springs, Colorado 80907
United States
Status: Recruiting Contact: Contact
Site Public Contact
719-776-5774
clinicaltrials@sfmc-gi.org
Facility: Rocky Mountain Cancer Centers-Penrose
Colorado Springs, Colorado 80907
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
308-398-6518
clinicaltrials@sfmc-gi.org
Facility: Saint Francis Cancer Center
Colorado Springs, Colorado 80923
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org
Facility: Porter Adventist Hospital
Denver, Colorado 80210
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
308-398-6518
clinicaltrials@sfmc-gi.org
Facility: Mercy Medical Center
Durango, Colorado 81301
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
info@westernstatesncorp.org
Facility: Southwest Oncology PC
Durango, Colorado 81301
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
308-398-6518
clinicaltrials@sfmc-gi.org
Facility: Saint Anthony Hospital
Lakewood, Colorado 80228
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org
Facility: Littleton Adventist Hospital
Littleton, Colorado 80122
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
303-777-2663
shelley.a.clark@kp.org
Facility: Longmont United Hospital
Longmont, Colorado 80501
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
eslinget@slhs.org
Facility: Rocky Mountain Cancer Centers-Longmont
Longmont, Colorado 80501
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
308-398-6518
eslinget@slhs.org
Facility: Parker Adventist Hospital
Parker, Colorado 80138
United States
Status: Recruiting Contact: Contact
Site Public Contact
954-267-7748
eslinget@slhs.org
Facility: Saint Mary Corwin Medical Center
Pueblo, Colorado 81004
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
808-432-5195
eslinget@slhs.org
Facility: Holy Cross Hospital
Fort Lauderdale, Florida 33308
United States
Status: Recruiting Contact: Contact
Site Public Contact
208-381-2774
eslinget@slhs.org
Facility: Kaiser Permanente Moanalua Medical Center
Honolulu, Hawaii 96819
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
208-381-2774
Cancer.Research@rushcopley.com
Facility: Saint Luke's Cancer Institute - Boise
Boise, Idaho 83712
United States
Status: Recruiting Contact: Contact
Site Public Contact
208-381-2774
andersonj@illinoiscancercare.com
Facility: Saint Luke's Cancer Institute - Fruitland
Fruitland, Idaho 83619
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
208-381-2774
andersonj@illinoiscancercare.com
Facility: Saint Luke's Cancer Institute - Meridian
Meridian, Idaho 83642
United States
Status: Recruiting Contact: Contact
Site Public Contact
208-381-2774
clinical.research@sih.net
Facility: Saint Luke's Cancer Institute - Nampa
Nampa, Idaho 83686
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
618-463-5623
clinical.research@sih.net
Facility: Saint Luke's Cancer Institute - Twin Falls
Twin Falls, Idaho 83301
United States
Status: Recruiting Contact: Contact
Site Public Contact
630-978-6212
andersonj@illinoiscancercare.com
Facility: Saint Anthony's Health
Alton, Illinois 62002
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
309-243-3605
morganthaler.jodi@mhsil.com
Facility: Rush - Copley Medical Center
Aurora, Illinois 60504
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
Research@carle.com
Facility: Illinois CancerCare-Bloomington
Bloomington, Illinois 61704
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
618-457-5200
morganthaler.jodi@mhsil.com
Facility: Illinois CancerCare-Canton
Canton, Illinois 61520
United States
Status: Recruiting Contact: Contact
Site Public Contact
618-985-3333
morganthaler.jodi@mhsil.com
Facility: Memorial Hospital of Carbondale
Carbondale, Illinois 62902
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
309-243-3605
Research@carle.com
Facility: SIH Cancer Institute
Carterville, Illinois 62918
United States
Status: Recruiting Contact: Contact
Site Public Contact
217-876-4762
morganthaler.jodi@mhsil.com
Facility: Illinois CancerCare-Carthage
Carthage, Illinois 62321
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
800-446-5532
andersonj@illinoiscancercare.com
Facility: Centralia Oncology Clinic
Centralia, Illinois 62801
United States
Status: Recruiting Contact: Contact
Site Public Contact
217-876-4762
andersonj@illinoiscancercare.com
Facility: Carle on Vermilion
Danville, Illinois 61832
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
217-876-4762
andersonj@illinoiscancercare.com
Facility: Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois 62526
United States
Status: Recruiting Contact: Contact
Site Public Contact
815-285-7800
andersonj@illinoiscancercare.com
Facility: Decatur Memorial Hospital
Decatur, Illinois 62526
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
800-446-5532
Research@carle.com
Facility: Illinois CancerCare-Dixon
Dixon, Illinois 61021
United States
Status: Recruiting Contact: Contact
Site Public Contact
217-876-4762
morganthaler.jodi@mhsil.com
Facility: Carle Physician Group-Effingham
Effingham, Illinois 62401
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
309-243-3605
andersonj@illinoiscancercare.com
Facility: Crossroads Cancer Center
Effingham, Illinois 62401
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com
Facility: Illinois CancerCare-Eureka
Eureka, Illinois 61530
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
309-344-2831
andersonj@illinoiscancercare.com
Facility: Illinois CancerCare-Galesburg
Galesburg, Illinois 61401
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
andersonj@illinoiscancercare.com
Facility: Western Illinois Cancer Treatment Center
Galesburg, Illinois 61401
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
309-243-3605
andersonj@illinoiscancercare.com
Facility: Illinois CancerCare-Kewanee Clinic
Kewanee, Illinois 61443
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-446-5532
andersonj@illinoiscancercare.com
Facility: Illinois CancerCare-Macomb
Macomb, Illinois 61455
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
618-242-4600
Research@carle.com
Facility: Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois 61938
United States
Status: Recruiting Contact: Contact
Site Public Contact
217-876-4762
Research@carle.com
Facility: Good Samaritan Regional Health Center
Mount Vernon, Illinois 62864
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
309-243-3605
andersonj@illinoiscancercare.com
Facility: Cancer Care Center of O'Fallon
O'Fallon, Illinois 62269
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
Cancer.Research@rushcopley.com
Facility: Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois 61350
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
309-243-3605
ctsucontact@westat.com
Facility: Illinois CancerCare-Pekin
Pekin, Illinois 61554
United States
Status: Recruiting Contact: Contact
Site Public Contact
309-243-3605
ksoder@mcfarlandclinic.com
Facility: Illinois CancerCare-Peoria
Peoria, Illinois 61615
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
309-243-3605
sbenson@iora.org
Facility: Methodist Medical Center of Illinois
Peoria, Illinois 61636
United States
Status: Recruiting Contact: Contact
Site Public Contact
815-664-4141
clinicaltrials@sfmc-gi.org
Facility: Illinois CancerCare-Peru
Peru, Illinois 61354
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
309-243-3605
clinicaltrials@sfmc-gi.org
Facility: Valley Radiation Oncology
Peru, Illinois 61354
United States
Status: Recruiting Contact: Contact
Site Public Contact
217-545-7929
clinicaltrials@sfmc-gi.org
Facility: Illinois CancerCare-Princeton
Princeton, Illinois 61356
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
800-444-7541
clinicaltrials@sfmc-gi.org
Facility: Southern Illinois University School of Medicine
Springfield, Illinois 62702
United States
Status: Recruiting Contact: Contact
Site Public Contact
217-788-3528
clinicaltrials@sfmc-gi.org
Facility: Springfield Clinic
Springfield, Illinois 62702
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
800-446-5532
clinicaltrials@sfmc-gi.org
Facility: Memorial Medical Center
Springfield, Illinois 62781
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-446-5532
clinicaltrials@sfmc-gi.org
Facility: Carle Cancer Center
Urbana, Illinois 61801
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
309-243-3605
aroland@kccop.org
Facility: The Carle Foundation Hospital
Urbana, Illinois 61801
United States
Status: Recruiting Contact: Contact
Site Public Contact
630-978-6212
aroland@kccop.org
Facility: Illinois CancerCare - Washington
Washington, Illinois 61571
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
888-823-5923
clinicaltrials@sfmc-gi.org
Facility: Rush-Copley Healthcare Center
Yorkville, Illinois 60560
United States
Status: Recruiting Contact: Contact
Site Public Contact
515-956-4132
clinicaltrials@sfmc-gi.org
Facility: Baptist Health Floyd
New Albany, Indiana 47150
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
515-239-4734
clinicaltrials@sfmc-gi.org
Facility: Mary Greeley Medical Center
Ames, Iowa 50010
United States
Status: Recruiting Contact: Contact
Site Public Contact
515-956-4132
clinicaltrials@sfmc-gi.org
Facility: McFarland Clinic PC - Ames
Ames, Iowa 50010
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
515-689-7658
clinicaltrials@sfmc-gi.org
Facility: McFarland Clinic PC-Boone
Boone, Iowa 50036
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org
Facility: Saint Anthony Regional Hospital
Carroll, Iowa 51401
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
308-398-6518
Cbcresearch@bhsi.com
Facility: Medical Oncology and Hematology Associates-West Des Moines
Clive, Iowa 50325
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
clinicaltrials@sfmc-gi.org
Facility: Mercy Cancer Center-West Lakes
Clive, Iowa 50325
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
308-398-6518
clinicaltrials@sfmc-gi.org
Facility: Alegent Health Mercy Hospital
Council Bluffs, Iowa 51503
United States
Status: Recruiting Contact: Contact
Site Public Contact
515-241-6727
clinicaltrials@sfmc-gi.org
Facility: Greater Regional Medical Center
Creston, Iowa 50801
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
515-282-2921
emede1@lsuhsc.edu
Facility: Iowa Methodist Medical Center
Des Moines, Iowa 50309
United States
Status: Recruiting Contact: Contact
Site Public Contact
515-282-2200
emede1@lsuhsc.edu
Facility: Medical Oncology and Hematology Associates-Des Moines
Des Moines, Iowa 50309
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
308-398-6518
emede1@lsuhsc.edu
Facility: Broadlawns Medical Center
Des Moines, Iowa 50314
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
stephanie.couch@stjoeshealth.org
Facility: Medical Oncology and Hematology Associates-Laurel
Des Moines, Iowa 50314
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib
515-241-8704
stephanie.couch@stjoeshealth.org
Facility: Mercy Medical Center - Des Moines
Des Moines, Iowa 50314
United States
Status: Recruiting Contact: Contact
Site Public Contact
515-956-4132
stephanie.couch@stjoeshealth.org
Facility: Iowa Lutheran Hospital
Des Moines, Iowa 50316
United States
Status: Recruiting Contact: Principal Investigator
Andrea L. Harzstark
515-574-8302
CTOResearch@hfhs.org
Facility: McFarland Clinic PC-Trinity Cancer Center
Fort Dodge, Iowa 50501
United States
Status: Recruiting Contact: Contact
Site Public Contact
515-956-4132
stephanie.couch@stjoeshealth.org
Facility: Trinity Regional Medical Center
Fort Dodge, Iowa 50501
United States
Status: Recruiting Contact: Principal Investigator
Alison K. Conlin
515-956-4132
stephanie.couch@stjoeshealth.org
Facility: McFarland Clinic PC-Jefferson
Jefferson, Iowa 50129
United States
Status: Recruiting Contact: Contact
Site Public Contact
515-343-1000
stephanie.couch@stjoeshealth.org
Facility: McFarland Clinic PC-Marshalltown
Marshalltown, Iowa 50158
United States
Status: Recruiting Contact: Principal Investigator
Alison K. Conlin
308-398-6518
stephanie.couch@stjoeshealth.org
Facility: Methodist West Hospital
West Des Moines, Iowa 50266-7700
United States
Status: Recruiting Contact: Contact
Site Public Contact
913-948-5588
stephanie.couch@stjoeshealth.org
Facility: Mercy Medical Center-West Lakes
West Des Moines, Iowa 50266
United States
Status: Recruiting Contact: Principal Investigator
Alison K. Conlin
913-948-5588
stephanie.couch@stjoeshealth.org
Facility: Central Care Cancer Center - Garden City
Garden City, Kansas 67846
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
stephanie.couch@stjoeshealth.org
Facility: Central Care Cancer Center - Great Bend
Great Bend, Kansas 67530
United States
Status: Recruiting Contact: Principal Investigator
Alison K. Conlin
859-523-1934
CTOResearch@hfhs.org
Facility: Flaget Memorial Hospital
Bardstown, Kentucky 40004
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
CTOResearch@hfhs.org
Facility: Baptist Health Corbin
Corbin, Kentucky 40701
United States
Status: Recruiting Contact: Principal Investigator
Alison K. Conlin
859-260-6425
CTOResearch@hfhs.org
Facility: Commonwealth Cancer Center-Corbin
Corbin, Kentucky 40701
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
stephanie.couch@stjoeshealth.org
Facility: Baptist Health Lexington
Lexington, Kentucky 40503
United States
Status: Recruiting Contact: Principal Investigator
Jay W. Carlson
308-398-6518
stephanie.couch@stjoeshealth.org
Facility: Saint Joseph Radiation Oncology Resource Center
Lexington, Kentucky 40504
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
stephanie.couch@stjoeshealth.org
Facility: Saint Joseph Hospital East
Lexington, Kentucky 40509
United States
Status: Recruiting Contact: Principal Investigator
Vamsi K. Vasireddy
308-398-6518
stephanie.couch@stjoeshealth.org
Facility: Saint Joseph London
London, Kentucky 40741
United States
Status: Recruiting Contact: Contact
Site Public Contact
502-897-8592
stephanie.couch@stjoeshealth.org
Facility: Jewish Hospital
Louisville, Kentucky 40202
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
308-398-6518
stephanie.couch@stjoeshealth.org
Facility: Baptist Health Louisville
Louisville, Kentucky 40207
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
stephanie.couch@stjoeshealth.org
Facility: Saints Mary and Elizabeth Hospital
Louisville, Kentucky 40215
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
800-733-2312
stephanie.couch@stjoeshealth.org
Facility: Jewish Hospital Medical Center Northeast
Louisville, Kentucky 40245
United States
Status: Recruiting Contact: Contact
Site Public Contact
270-575-2928
stephanie.couch@stjoeshealth.org
Facility: Baptist Health Madisonville/Merle Mahr Cancer Center
Madisonville, Kentucky 42431
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
308-398-6518
CTOResearch@hfhs.org
Facility: Baptist Health Paducah
Paducah, Kentucky 42003
United States
Status: Recruiting Contact: Contact
Site Public Contact
504-210-3539
stephanie.couch@stjoeshealth.org
Facility: Jewish Hospital Medical Center South
Shepherdsville, Kentucky 40165
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
504-210-3539
stephanie.couch@stjoeshealth.org
Facility: East Jefferson General Hospital
Metairie, Louisiana 70006
United States
Status: Recruiting Contact: Contact
Site Public Contact
504-210-3539
stephanie.couch@stjoeshealth.org
Facility: LSU Healthcare Network / Metairie Multi-Specialty Clinic
Metairie, Louisiana 70006
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
877-442-3324
stephanie.couch@stjoeshealth.org
Facility: Louisiana State University Health Science Center
New Orleans, Louisiana 70112
United States
Status: Recruiting Contact: Contact
Site Public Contact
877-442-3324
stephanie.couch@stjoeshealth.org
Facility: Dana-Farber Cancer Institute
Boston, Massachusetts 02215
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
517-265-0116
stephanie.couch@stjoeshealth.org
Facility: Dana-Farber Cancer Institute - Chestnut Hill
Newton, Massachusetts 02467
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
CTOResearch@hfhs.org
Facility: Hickman Cancer Center
Adrian, Michigan 49221
United States
Status: Recruiting Contact: Principal Investigator
Vamsi K. Vasireddy
734-712-3671
stephanie.couch@stjoeshealth.org
Facility: Saint Joseph Mercy Hospital
Ann Arbor, Michigan 48106
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
stephanie.couch@stjoeshealth.org
Facility: IHA Hematology Oncology Consultants-Brighton
Brighton, Michigan 48114
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
313-916-3721
stephanie.couch@stjoeshealth.org
Facility: Saint Joseph Mercy Brighton
Brighton, Michigan 48114
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
stephanie.couch@stjoeshealth.org
Facility: Henry Ford Cancer Institute-Downriver
Brownstown, Michigan 48183
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
734-712-3671
stephanie.couch@stjoeshealth.org
Facility: IHA Hematology Oncology Consultants-Canton
Canton, Michigan 48188
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
stephanie.couch@stjoeshealth.org
Facility: Saint Joseph Mercy Canton
Canton, Michigan 48188
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
734-712-3671
tpearce1@hfhs.org
Facility: Caro Cancer Center
Caro, Michigan 48723
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
stephanie.couch@stjoeshealth.org
Facility: IHA Hematology Oncology Consultants-Chelsea
Chelsea, Michigan 48118
United States
Status: Recruiting Contact: Principal Investigator
Vamsi K. Vasireddy
734-712-3671
stephanie.couch@stjoeshealth.org
Facility: Saint Joseph Mercy Chelsea
Chelsea, Michigan 48118
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
stephanie.couch@stjoeshealth.org
Facility: Hematology Oncology Consultants-Clarkston
Clarkston, Michigan 48346
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
313-916-3721
stephanie.couch@stjoeshealth.org
Facility: Newland Medical Associates-Clarkston
Clarkston, Michigan 48346
United States
Status: Recruiting Contact: Contact
Site Public Contact
313-916-3721
stephanie.couch@stjoeshealth.org
Facility: Henry Ford Macomb Hospital-Clinton Township
Clinton Township, Michigan 48038
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
313-916-3721
stephanie.couch@stjoeshealth.org
Facility: Henry Ford Medical Center-Fairlane
Dearborn, Michigan 48126
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
stephanie.couch@stjoeshealth.org
Facility: Henry Ford Hospital
Detroit, Michigan 48202
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
734-712-3671
CTOResearch@hfhs.org
Facility: Ascension Saint John Hospital
Detroit, Michigan 48236
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
stephanie.couch@stjoeshealth.org
Facility: Great Lakes Cancer Management Specialists-Doctors Park
East China Township, Michigan 48054
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
734-712-3671
stephanie.couch@stjoeshealth.org
Facility: Genesee Cancer and Blood Disease Treatment Center
Flint, Michigan 48503
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
stephanie.couch@stjoeshealth.org
Facility: Genesee Hematology Oncology PC
Flint, Michigan 48503
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
734-712-3671
OncologyClinicalTrialsFargo@sanfordhealth.org
Facility: Genesys Hurley Cancer Institute
Flint, Michigan 48503
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
mmcorc@healthpartners.com
Facility: Hurley Medical Center
Flint, Michigan 48503
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
734-712-3671
mmcorc@healthpartners.com
Facility: Academic Hematology Oncology Specialists
Grosse Pointe Woods, Michigan 48236
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
mmcorc@healthpartners.com
Facility: Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
Grosse Pointe Woods, Michigan 48236
United States
Status: Recruiting Contact: Principal Investigator
Vamsi K. Vasireddy
313-916-3721
mmcorc@healthpartners.com
Facility: Michigan Breast Specialists-Grosse Pointe Woods
Grosse Pointe Woods, Michigan 48236
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
mmcorc@healthpartners.com
Facility: Allegiance Health
Jackson, Michigan 49201
United States
Status: Recruiting Contact: Principal Investigator
Jay W. Carlson
734-712-3671
mmcorc@healthpartners.com
Facility: Sparrow Hospital
Lansing, Michigan 48912
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
mmcorc@healthpartners.com
Facility: Hope Cancer Clinic
Livonia, Michigan 48154
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
734-712-3671
mmcorc@healthpartners.com
Facility: Saint Mary Mercy Hospital
Livonia, Michigan 48154
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
mmcorc@healthpartners.com
Facility: Great Lakes Cancer Management Specialists-Macomb Medical Campus
Macomb, Michigan 48044
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
734-712-3671
mmcorc@healthpartners.com
Facility: Michigan Breast Specialists-Macomb Township
Macomb, Michigan 48044
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-444-3561
mmcorc@healthpartners.com
Facility: Saint Mary's Oncology/Hematology Associates of Marlette
Marlette, Michigan 48453
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
313-916-3721
mmcorc@healthpartners.com
Facility: Toledo Clinic Cancer Centers-Monroe
Monroe, Michigan 48162
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
mmcorc@healthpartners.com
Facility: Henry Ford Medical Center-Columbus
Novi, Michigan 48377
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
734-712-3671
mmcorc@healthpartners.com
Facility: 21st Century Oncology-Pontiac
Pontiac, Michigan 48341
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
mmcorc@healthpartners.com
Facility: Hope Cancer Center
Pontiac, Michigan 48341
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
734-712-3671
mmcorc@healthpartners.com
Facility: Newland Medical Associates-Pontiac
Pontiac, Michigan 48341
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
coborncancercenter@centracare.com
Facility: Saint Joseph Mercy Oakland
Pontiac, Michigan 48341
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
734-712-3671
mmcorc@healthpartners.com
Facility: Ascension Saint Mary's Hospital
Saginaw, Michigan 48601
United States
Status: Recruiting Contact: Contact
Site Public Contact
313-916-1784
mmcorc@healthpartners.com
Facility: Oncology Hematology Associates of Saginaw Valley PC
Saginaw, Michigan 48604
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
734-712-3671
mmcorc@healthpartners.com
Facility: Henry Ford Macomb Health Center - Shelby Township
Shelby, Michigan 48315
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
mmcorc@healthpartners.com
Facility: Bhadresh Nayak MD PC-Sterling Heights
Sterling Heights, Michigan 48312
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
734-712-3671
mmcorc@healthpartners.com
Facility: Ascension Saint Joseph Hospital
Tawas City, Michigan 48764
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
mmcorc@healthpartners.com
Facility: Advanced Breast Care Center PLLC
Warren, Michigan 48088
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
734-712-3671
mmcorc@healthpartners.com
Facility: Great Lakes Cancer Management Specialists-Macomb Professional Building
Warren, Michigan 48093
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
mmcorc@healthpartners.com
Facility: Macomb Hematology Oncology PC
Warren, Michigan 48093
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
734-712-3671
mmcorc@healthpartners.com
Facility: Michigan Breast Specialists-Warren
Warren, Michigan 48093
United States
Status: Recruiting Contact: Contact
Site Public Contact
313-916-3721
aroland@kccop.org
Facility: Saint John Macomb-Oakland Hospital
Warren, Michigan 48093
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
734-712-3671
sfmc@sfmc.net
Facility: Henry Ford West Bloomfield Hospital
West Bloomfield, Michigan 48322
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
info@siteman.wustl.edu
Facility: Saint Mary's Oncology/Hematology Associates of West Branch
West Branch, Michigan 48661
United States
Status: Recruiting Contact: Principal Investigator
Vamsi K. Vasireddy
734-712-3671
swooden@mail.crmc.org
Facility: Huron Gastroenterology PC
Ypsilanti, Michigan 48106
United States
Status: Recruiting Contact: Contact
Site Public Contact
218-333-5000
LJCrockett@freemanhealth.com
Facility: IHA Hematology Oncology Consultants-Ann Arbor
Ypsilanti, Michigan 48197
United States
Status: Recruiting Contact: Principal Investigator
Vamsi K. Vasireddy
952-993-1517
esmeralda.carrillo@mercy.net
Facility: Sanford Joe Lueken Cancer Center
Bemidji, Minnesota 56601
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
research@phelpshealth.org
Facility: Fairview Ridges Hospital
Burnsville, Minnesota 55337
United States
Status: Recruiting Contact: Principal Investigator
Bryan A. Faller
952-993-1517
linda.schumacher@mymlc.com
Facility: Minnesota Oncology - Burnsville
Burnsville, Minnesota 55337
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
info@siteman.wustl.edu
Facility: Cambridge Medical Center
Cambridge, Minnesota 55008
United States
Status: Recruiting Contact: Principal Investigator
Vamsi K. Vasireddy
952-993-1517
janet.lesko@mercy.net
Facility: Mercy Hospital
Coon Rapids, Minnesota 55433
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
info@siteman.wustl.edu
Facility: Fairview Southdale Hospital
Edina, Minnesota 55435
United States
Status: Recruiting Contact: Principal Investigator
Shawn Peterson
952-993-1517
info@siteman.wustl.edu
Facility: Unity Hospital
Fridley, Minnesota 55432
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
info@siteman.wustl.edu
Facility: Fairview Clinics and Surgery Center Maple Grove
Maple Grove, Minnesota 55369
United States
Status: Recruiting Contact: Principal Investigator
Debra M. Prow
952-993-1517
amy.hanneman@providence.org
Facility: Minnesota Oncology Hematology PA-Maplewood
Maplewood, Minnesota 55109
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
clinicaltrials@sfmc-gi.org
Facility: Saint John's Hospital - Healtheast
Maplewood, Minnesota 55109
United States
Status: Recruiting Contact: Principal Investigator
Debra M. Prow
952-993-1517
clinicaltrials@sfmc-gi.org
Facility: Abbott-Northwestern Hospital
Minneapolis, Minnesota 55407
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
clinicaltrials@sfmc-gi.org
Facility: Hennepin County Medical Center
Minneapolis, Minnesota 55415
United States
Status: Recruiting Contact: Principal Investigator
Debra M. Prow
952-993-1517
clinicaltrials@sfmc-gi.org
Facility: Health Partners Inc
Minneapolis, Minnesota 55454
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
clinicaltrials@sfmc-gi.org
Facility: Monticello Cancer Center
Monticello, Minnesota 55362
United States
Status: Recruiting Contact: Principal Investigator
Joshua Lukenbill
952-993-1517
clinicaltrials@sfmc-gi.org
Facility: New Ulm Medical Center
New Ulm, Minnesota 56073
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
clinicaltrials@sfmc-gi.org
Facility: Fairview Northland Medical Center
Princeton, Minnesota 55371
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
877-229-4907
LByatt@nmcca.org
Facility: North Memorial Medical Health Center
Robbinsdale, Minnesota 55422
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
askroswell@roswellpark.org
Facility: Coborn Cancer Center at Saint Cloud Hospital
Saint Cloud, Minnesota 56303
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
952-993-1517
McDowelE@upstate.edu
Facility: Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota 55416
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
jfields@cancersmoc.com
Facility: Regions Hospital
Saint Paul, Minnesota 55101
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
952-993-1517
jfields@cancersmoc.com
Facility: United Hospital
Saint Paul, Minnesota 55102
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
jfields@cancersmoc.com
Facility: Saint Francis Regional Medical Center
Shakopee, Minnesota 55379
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
605-312-3320
OncologyClinicalTrialsFargo@sanfordhealth.org
Facility: Lakeview Hospital
Stillwater, Minnesota 55082
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
OncologyClinicalTrialsFargo@sanfordhealth.org
Facility: Sanford Thief River Falls Medical Center
Thief River Falls, Minnesota 56701
United States
Status: Recruiting Contact: Principal Investigator
Joshua Lukenbill
952-993-1517
OncologyClinicalTrialsFargo@sanfordhealth.org
Facility: Ridgeview Medical Center
Waconia, Minnesota 55387
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
clinicaltrials@sfmc-gi.org
Facility: Rice Memorial Hospital
Willmar, Minnesota 56201
United States
Status: Recruiting Contact: Principal Investigator
Joshua Lukenbill
605-312-3320
clinicaltrials@sfmc-gi.org
Facility: Minnesota Oncology Hematology PA-Woodbury
Woodbury, Minnesota 55125
United States
Status: Recruiting Contact: Contact
Site Public Contact
952-993-1517
clinicaltrials@sfmc-gi.org
Facility: Sanford Cancer Center Worthington
Worthington, Minnesota 56187
United States
Status: Recruiting Contact: Principal Investigator
Joshua Lukenbill
601-815-6700
clinicaltrials@sfmc-gi.org
Facility: Fairview Lakes Medical Center
Wyoming, Minnesota 55092
United States
Status: Recruiting Contact: Contact
Site Public Contact
314-251-7058
ou-clinical-trials@ouhsc.edu
Facility: University of Mississippi Medical Center
Jackson, Mississippi 39216
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
913-948-5588
nosall@stcharleshealthcare.org
Facility: Saint Louis Cancer and Breast Institute-Ballwin
Ballwin, Missouri 63011
United States
Status: Recruiting Contact: Contact
Site Public Contact
573-334-2230
CanRsrchStudies@providence.org
Facility: Central Care Cancer Center - Bolivar
Bolivar, Missouri 65613
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
573-651-5550
CanRsrchStudies@providence.org
Facility: Saint Francis Medical Center
Cape Girardeau, Missouri 63703
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-600-3606
cherie.cox@bayareahospital.org
Facility: Southeast Cancer Center
Cape Girardeau, Missouri 63703
United States
Status: Recruiting Contact: Principal Investigator
Joshua Lukenbill
314-996-5569
CanRsrchStudies@providence.org
Facility: Siteman Cancer Center at West County Hospital
Creve Coeur, Missouri 63141
United States
Status: Recruiting Contact: Contact
Site Public Contact
573-632-4814
CanRsrchStudies@providence.org
Facility: Parkland Health Center - Farmington
Farmington, Missouri 63640
United States
Status: Recruiting Contact: Principal Investigator
Debra M. Prow
417-347-4030
CanRsrchStudies@providence.org
Facility: Capital Region Southwest Campus
Jefferson City, Missouri 65109
United States
Status: Recruiting Contact: Contact
Site Public Contact
417-556-3074
stephanie.couch@stjoeshealth.org
Facility: Freeman Health System
Joplin, Missouri 64804
United States
Status: Recruiting Contact: Principal Investigator
Joshua Lukenbill
573-458-7504
stephanie.couch@stjoeshealth.org
Facility: Mercy Hospital Joplin
Joplin, Missouri 64804
United States
Status: Recruiting Contact: Contact
Site Public Contact
573-458-6379
stephanie.couch@stjoeshealth.org
Facility: Delbert Day Cancer Institute at PCRMC
Rolla, Missouri 65401
United States
Status: Recruiting Contact: Principal Investigator
Debra M. Prow
816-271-7937
stephanie.couch@stjoeshealth.org
Facility: Mercy Clinic-Rolla-Cancer and Hematology
Rolla, Missouri 65401
United States
Status: Recruiting Contact: Contact
Site Public Contact
314-353-1870
OncologyClinicTrialsSF@sanfordhealth.org
Facility: Heartland Regional Medical Center
Saint Joseph, Missouri 64506
United States
Status: Recruiting Contact: Principal Investigator
Debra M. Prow
800-600-3606
OncologyClinicalTrialsSF@SanfordHealth.org
Facility: Saint Louis Cancer and Breast Institute-South City
Saint Louis, Missouri 63109
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-600-3606
afletcher@westclinic.com
Facility: Washington University School of Medicine
Saint Louis, Missouri 63110
United States
Status: Recruiting Contact: Principal Investigator
Joshua Lukenbill
314-996-5569
clinicaltrials@sfmc-gi.org
Facility: Mercy Hospital South
Saint Louis, Missouri 63128
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-600-3606
deidre.dillon@providence.org
Facility: Siteman Cancer Center-South County
Saint Louis, Missouri 63129
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
314-251-7066
lkey@peacehealth.org
Facility: Missouri Baptist Medical Center
Saint Louis, Missouri 63131
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-600-3606
clinicaltrials@sfmc-gi.org
Facility: Siteman Cancer Center at Christian Hospital
Saint Louis, Missouri 63136
United States
Status: Recruiting Contact: Principal Investigator
Jay W. Carlson
314-996-5569
conchitapurchase@chifranciscan.org
Facility: Mercy Hospital Saint Louis
Saint Louis, Missouri 63141
United States
Status: Recruiting Contact: Contact
Site Public Contact
417-269-4520
clinicaltrials@sfmc-gi.org
Facility: Siteman Cancer Center at Saint Peters Hospital
Saint Peters, Missouri 63376
United States
Status: Recruiting Contact: Principal Investigator
Jay W. Carlson
417-269-4520
deidre.dillon@providence.org
Facility: Sainte Genevieve County Memorial Hospital
Sainte Genevieve, Missouri 63670
United States
Status: Recruiting Contact: Contact
Site Public Contact
314-996-5569
PCRC-NCORP@Swedish.org
Facility: Mercy Hospital Springfield
Springfield, Missouri 65804
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
314-996-5569
clinicaltrials@sfmc-gi.org
Facility: CoxHealth South Hospital
Springfield, Missouri 65807
United States
Status: Recruiting Contact: Contact
Site Public Contact
636-390-1600
marilyn.birchman@providence.org
Facility: Missouri Baptist Sullivan Hospital
Sullivan, Missouri 63080
United States
Status: Recruiting Contact: Principal Investigator
Shawn Peterson
406-327-3118
clinicaltrials@sfmc-gi.org
Facility: Missouri Baptist Outpatient Center-Sunset Hills
Sunset Hills, Missouri 63127
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-5450
PCRC-NCORP@Swedish.org
Facility: Mercy Hospital Washington
Washington, Missouri 63090
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
308-398-6518
research@kadlecmed.org
Facility: Saint Patrick Hospital - Community Hospital
Missoula, Montana 59802
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
deidre.dillon@providence.org
Facility: CHI Health Saint Francis
Grand Island, Nebraska 68803
United States
Status: Recruiting Contact: Principal Investigator
Shawn Peterson
308-398-6518
clinicaltrials@sfmc-gi.org
Facility: CHI Health Good Samaritan
Kearney, Nebraska 68847
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
kmakin-bond@peacehealth.org
Facility: Saint Elizabeth Regional Medical Center
Lincoln, Nebraska 68510
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
308-398-6518
PCRC-NCORP@Swedish.org
Facility: Alegent Health Immanuel Medical Center
Omaha, Nebraska 68122
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
PCRC-NCORP@Swedish.org
Facility: Alegent Health Bergan Mercy Medical Center
Omaha, Nebraska 68124
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
308-398-6518
PCRC-NCORP@Swedish.org
Facility: Alegent Health Lakeside Hospital
Omaha, Nebraska 68130
United States
Status: Recruiting Contact: Contact
Site Public Contact
505-925-0366
lkey@peacehealth.org
Facility: Creighton University Medical Center
Omaha, Nebraska 68131
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
800-767-9355
deidre.dillon@providence.org
Facility: Midlands Community Hospital
Papillion, Nebraska 68046
United States
Status: Recruiting Contact: Contact
Site Public Contact
315-464-8230
clinicaltrials@sfmc-gi.org
Facility: University of New Mexico Cancer Center
Albuquerque, New Mexico 87102
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
800-862-2215
kmakin-bond@peacehealth.org
Facility: Roswell Park Cancer Institute
Buffalo, New York 14263
United States
Status: Recruiting Contact: Contact
Site Public Contact
315-464-5476
Cheryl.Dodd@providence.org
Facility: Upstate Cancer Center at Oneida
Oneida, New York 13421
United States
Status: Recruiting Contact: Principal Investigator
Shawn Peterson
919-587-9084
deidre.dillon@providence.org
Facility: Stony Brook University Medical Center
Stony Brook, New York 11794
United States
Status: Recruiting Contact: Contact
Site Public Contact
919-587-9084
oncology.clinical.trials@marshfieldresearch.org
Facility: State University of New York Upstate Medical University
Syracuse, New York 13210
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
910-587-9084
oncology.clinical.trials@marshfieldresearch.org
Facility: Southeastern Medical Oncology Center-Clinton
Clinton, North Carolina 28328
United States
Status: Recruiting Contact: Contact
Site Public Contact
701-323-5760
oncology.clinical.trials@marshfieldresearch.org
Facility: Southeastern Medical Oncology Center-Goldsboro
Goldsboro, North Carolina 27534
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
701-234-6161
research.institute@phci.org
Facility: Southeastern Medical Oncology Center-Jacksonville
Jacksonville, North Carolina 28546
United States
Status: Recruiting Contact: Contact
Site Public Contact
605-312-3320
mmcorc@healthpartners.com
Facility: Sanford Bismarck Medical Center
Bismarck, North Dakota 58501
United States
Status: Recruiting Contact: Principal Investigator
Shawn Peterson
800-437-4010
oncology.clinical.trials@marshfieldresearch.org
Facility: Sanford South University Medical Center
Fargo, North Dakota 58103
United States
Status: Recruiting Contact: Contact
Site Public Contact
701-323-5760
oncology.clinical.trials@marshfieldresearch.org
Facility: Southpointe-Sanford Medical Center Fargo
Fargo, North Dakota 58103
United States
Status: Recruiting Contact: Principal Investigator
Shawn Peterson
701-234-6161
Chanda.miller@phci.org
Facility: Sanford Medical Center Fargo
Fargo, North Dakota 58104
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
oncology.clinical.trials@marshfieldresearch.org
Facility: Sanford Broadway Medical Center
Fargo, North Dakota 58122
United States
Status: Recruiting Contact: Principal Investigator
Richard L. Deming
308-398-6518
Facility: Sanford Roger Maris Cancer Center
Fargo, North Dakota 58122
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
Facility: Good Samaritan Hospital - Cincinnati
Cincinnati, Ohio 45220
United States
Status: Recruiting Contact: Principal Investigator
Scott E. Delacroix
308-398-6518
Facility: Bethesda North Hospital
Cincinnati, Ohio 45242
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-444-3561
Facility: TriHealth Cancer Institute-Westside
Cincinnati, Ohio 45247
United States
Status: Recruiting Contact: Principal Investigator
Scott E. Delacroix
405-271-8777
Facility: TriHealth Cancer Institute-Anderson
Cincinnati, Ohio 45255
United States
Status: Recruiting Contact: Contact
Site Public Contact
405-752-3402
Facility: Toledo Clinic Cancer Centers-Toledo
Toledo, Ohio 43623
United States
Status: Recruiting Contact: Contact
Site Public Contact
541-706-2909
Facility: University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma 73104
United States
Status: Recruiting Contact: Principal Investigator
Xiao X. Wei
503-215-2614
Facility: Mercy Hospital Oklahoma City
Oklahoma City, Oklahoma 73120
United States
Status: Recruiting Contact: Contact
Site Public Contact
503-215-2614
Facility: Oklahoma Cancer Specialists and Research Institute-Tulsa
Tulsa, Oklahoma 74146
United States
Status: Recruiting Contact: Principal Investigator
Xiao X. Wei
541-269-8392
Facility: Saint Charles Health System
Bend, Oregon 97701
United States
Status: Recruiting Contact: Contact
Site Public Contact
503-215-2614
Facility: Clackamas Radiation Oncology Center
Clackamas, Oregon 97015
United States
Status: Recruiting Contact: Principal Investigator
Rex B. Mowat
503-215-2614
Facility: Providence Cancer Institute Clackamas Clinic
Clackamas, Oregon 97015
United States
Status: Recruiting Contact: Contact
Site Public Contact
503-215-2614
Facility: Bay Area Hospital
Coos Bay, Oregon 97420
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib
541-706-2909
Facility: Providence Newberg Medical Center
Newberg, Oregon 97132
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
Facility: Providence Portland Medical Center
Portland, Oregon 97213
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib
734-712-3671
Facility: Providence Saint Vincent Medical Center
Portland, Oregon 97225
United States
Status: Recruiting Contact: Contact
Site Public Contact
734-712-3671
Facility: Saint Charles Health System-Redmond
Redmond, Oregon 97756
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib
734-712-3671
Facility: Lehigh Valley Hospital-Cedar Crest
Allentown, Pennsylvania 18103
United States
Status: Recruiting Contact: Contact
Site Public Contact
605-312-3320
Facility: Lehigh Valley Hospital - Muhlenberg
Bethlehem, Pennsylvania 18017
United States
Status: Recruiting Contact: Principal Investigator
Ding Wang
605-312-3320
Facility: Pocono Medical Center
East Stroudsburg, Pennsylvania 18301
United States
Status: Recruiting Contact: Contact
Site Public Contact
901-683-0055
Facility: Lehigh Valley Hospital-Hazleton
Hazleton, Pennsylvania 18201
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib
308-398-6518
Facility: Sanford Cancer Center Oncology Clinic
Sioux Falls, South Dakota 57104
United States
Status: Recruiting Contact: Contact
Site Public Contact
360-412-8958
Facility: Sanford USD Medical Center - Sioux Falls
Sioux Falls, South Dakota 57117-5134
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib
360-788-8238
Facility: The West Clinic - Wolf River
Germantown, Tennessee 38138
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
Facility: Saint Joseph Regional Cancer Center
Bryan, Texas 77802
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib
888-825-3227
Facility: Providence Regional Cancer System-Aberdeen
Aberdeen, Washington 98520
United States
Status: Recruiting Contact: Contact
Site Public Contact
308-398-6518
Facility: PeaceHealth Saint Joseph Medical Center
Bellingham, Washington 98225
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib
360-412-8958
Facility: Harrison HealthPartners Hematology and Oncology-Bremerton
Bremerton, Washington 98310
United States
Status: Recruiting Contact: Contact
Site Public Contact
206-215-3086
Facility: Harrison Medical Center
Bremerton, Washington 98310
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib
308-398-6518
Facility: Highline Medical Center-Main Campus
Burien, Washington 98166
United States
Status: Recruiting Contact: Contact
Site Public Contact
425-261-3529
Facility: Providence Regional Cancer System-Centralia
Centralia, Washington 98531
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib
308-398-6518
Facility: Swedish Cancer Institute-Edmonds
Edmonds, Washington 98026
United States
Status: Recruiting Contact: Contact
Site Public Contact
206-215-3086
Facility: Saint Elizabeth Hospital
Enumclaw, Washington 98022
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib
509-783-4637
Facility: Providence Regional Cancer Partnership
Everett, Washington 98201
United States
Status: Recruiting Contact: Contact
Site Public Contact
360-412-8958
Facility: Saint Francis Hospital
Federal Way, Washington 98003
United States
Status: Recruiting Contact: Principal Investigator
Ding Wang
308-398-6518
Facility: Swedish Cancer Institute-Issaquah
Issaquah, Washington 98029
United States
Status: Recruiting Contact: Contact
Site Public Contact
360-514-2016
Facility: Kadlec Clinic Hematology and Oncology
Kennewick, Washington 99336
United States
Status: Recruiting Contact: Principal Investigator
Ding Wang
206-215-3086
Facility: Providence Regional Cancer System-Lacey
Lacey, Washington 98503
United States
Status: Recruiting Contact: Contact
Site Public Contact
206-215-3086
Facility: Saint Clare Hospital
Lakewood, Washington 98499
United States
Status: Recruiting Contact: Principal Investigator
Ding Wang
206-215-3086
Facility: PeaceHealth Saint John Medical Center
Longview, Washington 98632
United States
Status: Recruiting Contact: Contact
Site Public Contact
360-788-8238
Facility: Swedish Medical Center-Ballard Campus
Seattle, Washington 98107
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib
360-514-3940
Facility: Swedish Medical Center-First Hill
Seattle, Washington 98122-4307
United States
Status: Recruiting Contact: Contact
Site Public Contact
509-897-5993
Facility: Swedish Medical Center-Cherry Hill
Seattle, Washington 98122-5711
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib
360-412-8958
Facility: PeaceHealth United General Medical Center
Sedro-Woolley, Washington 98284
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-782-8581
Facility: Providence Regional Cancer System-Shelton
Shelton, Washington 98584
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib
800-782-8581
Facility: Franciscan Research Center-Northwest Medical Plaza
Tacoma, Washington 98405
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-782-8581
Facility: PeaceHealth Southwest Medical Center
Vancouver, Washington 98664
United States
Status: Recruiting Contact: Contact
Site Public Contact
262-928-7878
Facility: Providence Saint Mary Regional Cancer Center
Walla Walla, Washington 99362
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib
800-782-8581
Facility: Providence Regional Cancer System-Yelm
Yelm, Washington 98597
United States
Status: Recruiting Contact: Contact
Site Public Contact
800-782-8581
Facility: Marshfield Medical Center-EC Cancer Center
Eau Claire, Wisconsin 54701
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib
262-928-7632
Facility: Marshfield Medical Center-Marshfield
Marshfield, Wisconsin 54449
United States
Status: Recruiting Contact: Contact
Site Public Contact
262-928-5539
Facility: Marshfield Clinic-Minocqua Center
Minocqua, Wisconsin 54548
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib
800-782-8581
Facility: ProHealth D N Greenwald Center
Mukwonago, Wisconsin 53149
United States
Status: Recruiting Contact: Contact
Site Public Contact

Facility: Cancer Center of Western Wisconsin
New Richmond, Wisconsin 54017
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib

Facility: ProHealth Oconomowoc Memorial Hospital
Oconomowoc, Wisconsin 53066
United States
Status: Recruiting Contact: Contact
Site Public Contact

Facility: Marshfield Medical Center-Rice Lake
Rice Lake, Wisconsin 54868
United States
Status: Recruiting Contact: Principal Investigator
Ding Wang

Facility: Marshfield Clinic Stevens Point Center
Stevens Point, Wisconsin 54482
United States
Status: Recruiting Contact: Contact
Site Public Contact

Facility: ProHealth Waukesha Memorial Hospital
Waukesha, Wisconsin 53188
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib

Facility: UW Cancer Center at ProHealth Care
Waukesha, Wisconsin 53188
United States
Status: Recruiting Contact: Contact
Site Public Contact

Facility: Marshfield Medical Center - Weston
Weston, Wisconsin 54476
United States
Status: Recruiting Contact: Principal Investigator
Elie G. Dib