Treatment Matrix

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Targeted therapy


Metastatic Bladder Cancer (includes T4 tumors)

Treatment Category:

Targeted therapy


Targeted therapy

Suitable for:

Suitable for people with advanced or metastatic bladder cancer, if specific mutations are present in the tumor genetic material and the cancer has continued to progress after treatment with other therapeutics, such as chemotherapy

How it works:

Works by targeting a specific genetic mutation that helps bladder cancer cells to grow. The targeted therapy blocks this part of the bladder cancer cell, which stops it growing

How it is typically used:

Used in people with advanced or metastatic bladder cancer in cases where the cancer has continued to progress after treatment with other therapies such as chemotherapy

How it is administered:

Taken as a pill

Side effects:
  • Mouth sores
  • Fatigue
  • Impacts on kidney or liver function
  • Diarrhea
  • Dry mouth
  • Changes in fingernails/toenails
  • Changes in blood mineral levels
  • Loss of appetite
  • Changes to sense of taste
  • Anemia
  • Dry skin
  • Dry eyes
  • Hair loss

Disclaimer: Information and services provided by the Bladder Cancer Advocacy Network (BCAN) are for informational purposes only. The information and services are not intended to be substitutes for professional medical advice, diagnosis or treatment. If you are ill, or suspect that you are ill, seek professional medical attention immediately! BCAN does not recommend or endorse any specific physicians, treatments, procedures or products even though they may be mentioned on this site.

  • You can search for a clinical trial by bladder cancer disease state, state of residence and you can also look for trials nearest to you.

  • Our interactive map shows the total numbers of cases anticipated in each of the 50 states as well as additional helpful bladder cancer resources in each state.